Evidence map›Paper›PMID 42634688›Full record

ArticlemicroPublication biology2026

The miRNA Argonaute protein, ALG-2, maintains neurobehaviors in adult

Ava Chon, Runtian Jiang, Yuxuan Guo, Yamin K Phyu, Lilly M Goldberg, Erin C Schiksnis, Amy E Pasquinelli, Sierra D Palumbos

Abstract read
In one paragraph

Article in microPublication biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ava ChonBiology, Swarthmore College, Swarthmore, PA, United States.
Runtian JiangMolecular Biology, UC San Diego, San Diego, CA, United States.
Yuxuan GuoBiology, Swarthmore College, Swarthmore, PA, United States.
Yamin K PhyuBiology, Swarthmore College, Swarthmore, PA, United States.
Lilly M GoldbergBiology, Swarthmore College, Swarthmore, PA, United States.
Erin C SchiksnisMolecular Biology, UC San Diego, San Diego, CA, United States.
Amy E PasquinelliMolecular Biology, UC San Diego, San Diego, CA, United States.
Sierra D PalumbosBiology, Swarthmore College, Swarthmore, PA, United States.

Funding

GENETIC MECHANISMS AND REGULATIONT32GM007240 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAMPTON, RANDOLPH Y. · 1985 to 2019
$23.8M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Biogenesis and Function of Regulatory RNAsR35GM127012 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AMY E. PASQUINELLI · 2018 to 2026
$3.6M
NIGMS NIH HHS R35 GM127012NIGMS NIH HHS T32 GM007240NIH HHS P40 OD010440
6 · The paper itself

Abstract

microRNAs (miRNAs) are short, non-coding RNAs essential for gene regulation in many different processes, including neuronal development. However, the role of the miRNA pathway in maintaining neuronal health throughout aging is less understood. Here, we ask how the miRNA pathway in adulthood impacts neurobehaviors in

Identifiers

PMID42634688
PMCPMC13499938

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.