Evidence map›Paper›PMID 42634660›Full record

ArticlePharmacogenomics and personalized medicine2026

Association Between

Xuanwei Huang, Yuxin Tan, Qingling Gu, Liang Zhang, Haofeng Chen, Xiaolin Ruan, Xiangcheng Zhou, Zhongxing Wang, Faling Xue, Jie Jia

Abstract read
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xuanwei Huang *Department of Anesthesia, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.ORCID 0000-0001-5203-1907
Yuxin Tan *Department of Anesthesia, Guangdong Women and Children Hospital, Guangzhou, Guangdong, People's Republic of China.
Qingling GuSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Liang ZhangTranslational Medicine Center, Guangdong Women and Children Hospital, Guangzhou, Guangdong, People's Republic of China.
Haofeng ChenDepartment of Anesthesia, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Xiaolin RuanClinical Laboratory, Guangdong Women and Children Hospital, Guangzhou, Guangdong, People's Republic of China.
Xiangcheng ZhouTranslational Medicine Center, Guangdong Women and Children Hospital, Guangzhou, Guangdong, People's Republic of China.
Zhongxing WangDepartment of Anesthesia, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.ORCID 0000-0003-4490-6202
Faling XueDepartment of Anesthesia, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Jie JiaDepartment of Anesthesia, Guangdong Women and Children Hospital, Guangzhou, Guangdong, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Propofol, a commonly used intravenous sedative in general anesthesia, exhibits significant inter-individual variability in clinical effects; however, the underlying mechanisms remain uncertain. We aimed to assess the association between the UGT1A9 rs13418420 polymorphism and individual propofol response, as assessed by the time required for the bispectral index (BIS) to decrease to 60. Patients and Methods: A total of 75 Chinese female patients undergoing painless abortion, cervical conization, or hysteroscopy under intravenous anesthesia without endotracheal intubation were recruited. Based on bioinformatic analysis and our preliminary sequencing experiments in the Chinese population, Results: Our results revealed that patients with the TT genotype of Conclusion: Patients carrying the TT genotype of

Indexed as

gene polymorphismintravenous general anesthesiapharmacogenomicspropofolUGT1A9 rs13418420

Identifiers

PMID42634660
PMCPMC13500018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.