Evidence map›Paper›PMID 42634460›Full record

ReviewZhongguo fei ai za zhi = Chinese journal of lung cancer2026

[Research Progress on Molecular Mechanisms and Precision Diagnosis 
and Treatment of Spinal Organotropic Metastasis in Lung Adenocarcinoma].

Hongyang Fu, Yitong She, Manglai Li, Yiming Du, Yong Zhu

Abstract readReviewEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Review in Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hongyang FuInner Mongolia Medical University, Hohhot 010010, China.
Yitong SheInner Mongolia Medical University, Hohhot 010010, China.
Manglai LiPeking University Cancer Hospital Inner Mongolia Hospital, Hohhot 010010, China.
Yiming DuInner Mongolia Medical University, Hohhot 010010, China.
Yong ZhuPeking University Cancer Hospital Inner Mongolia Hospital, Hohhot 010010, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell lung cancer (NSCLC), with a high incidence of spinal metastasis and poor prognosis. Spinal metastasis of LUAD is not merely a simple bone metastasis but a directed metastasis process mediated by the anatomical characteristics of the spine, microenvironment specificity, and molecular regulatory mechanisms. However, current research mainly focuses on general bone metastasis, and a dedicated mechanism and precise diagnosis and treatment system for spinal-directed metastasis have not yet been established. Therefore, this article systematically elaborates on the molecular mechanisms of LUAD spinal-directed metastasis from three key aspects: metastatic potential, microenvironment regulation, and metastasis pathways. Combined with the clinical characteristics of spinal metastasis and the current research deficiencies, it provides new ideas for basic research and clinical precise prevention and treatment of LUAD spinal metastasis.
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Indexed as

AdenocarcinomaAdenocarcinoma of LungLung NeoplasmsPrecision MedicineSpinal NeoplasmsAnimalsHumansLung neoplasmsPrecision therapySpinal microenvironmentSpinal organotropic metastasis

Identifiers

PMID42634460
PMCPMC13482746

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.