ArticleYonsei medical journal2026
Predicting Functional Prognosis in Supratentorial Stroke Using [¹⁸F]Fluoro-2-deoxy-D-glucose Positron Emission Tomography.
Article in Yonsei medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeCerebral metabolic activity following stroke plays a crucial role in neurological recovery. This study aimed to investigate whether decreased cerebral metabolic activity, quantified by the asymmetry index (AI) using [¹⁸F]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET), predicts functional prognosis at 3 and 6 months in patients with supratentorial stroke. MATERIALS AND
methodsForty patients with a first-time supratentorial stroke were enrolled. Neurological status was quantified using the National Institutes of Health Stroke Scale (NIHSS) and the Motricity Index (MI) at baseline (time of PET acquisition), and at 3 and 6 months after stroke onset. Using PET imaging, metabolic AI was calculated for both the cerebral and cerebellar hemispheres. Correlations between AI and neurologic outcomes were analyzed according to the timing of PET acquisition, classified as the acute (1-14 days) or subacute (15-60 days) phases.
resultsIn the subacute group, cerebral AI showed significant correlations with NIHSS scores at baseline (r=0.511,
conclusionCerebral metabolic asymmetry measured during the subacute phase of supratentorial stroke is a significant predictor of long-term neurological outcomes at 3 and 6 months.
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