Evidence map›Paper›PMID 42634047›Full record

ArticleClinical oral investigations2026

Developmental enamel defects and hypomineralized second primary molars among preschool children in Kuwait: associations with caries severity and oral health-related quality of life.

Abrar Alanzi, Sahar Behzadi, Jagan Baskaradoss, Aishah Alsumait

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Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Abrar AlanziDepartment of Developmental and Preventive Sciences, College of Dentistry, Kuwait University, Sabah Al Salem University City, Kuwait City, Kuwait. Abrar.alanzi@ku.edu.kw.ORCID http://orcid.org/0000-0002-5897-4970
Sahar BehzadiMinistry of Health, Sulaibkhat, Kuwait.
Jagan BaskaradossDepartment of Developmental and Preventive Sciences, College of Dentistry, Kuwait University, Sabah Al Salem University City, Kuwait City, Kuwait.
Aishah AlsumaitMinistry of Health, Sulaibkhat, Kuwait.

Funding

Kuwait University DD01/22
6 · The paper itself

Abstract

objectivesto determine the prevalence and distribution of developmental enamel defects (DDEs), including hypomineralized second primary molars (HSPMs) among preschool children, and to evaluate their associations with caries experience, clinical consequences of untreated caries, and oral health-related quality of life. MATERIALS AND

methodsthis cross-sectional population-based study included kindergarten children. Dental caries was evaluated using dmft/dmfs indices, and clinical consequences of untreated caries were assessed by pufa index. DDEs were recorded by the modified DDEs index, and HSPMs were diagnosed according to European Academy of Paediatric Dentistry criteria. OHRQoL was evaluated by the validated Arabic Early Childhood Oral Health Impact Scale (A-ECOHIS).

resultsDDEs were identified in 66.2% of children, with combination defects (29.9%) and demarcated opacities (25.5%) being the most prevalent subtypes. HSPMs were present in 20.0%. Children with DDEs had significantly higher odds of dental caries than those without DDEs (adjusted OR = 2.00; 95% CI: 1.48-2.70). Among DDEs subtypes, enamel hypoplasia (EH) showed the strongest association with dental caries (adjusted OR = 3.50) and clinical consequences of untreated caries (pufa > 0, adjusted OR = 2.34). HSPM presence was also associated with higher odds of caries (adjusted OR = 2.42). EH was also significantly associated with higher child (p < 0.001) and family A-ECOHIS scores (p = 0.01). Severe HSPMs were significantly associated with higher child and family A-ECOHIS scores (p < 0.001).

conclusionsDevelopmental enamel defects, particularly enamel hypoplasia and hypomineralized second primary molars, are clinically relevant conditions associated with high caries experience, clinical consequences of untreated caries and poorer OHRQoL in preschool children.

Indexed as

Dental CariesDental Enamel HypomineralizationDental Enamel HypoplasiaDevelopmental Defects of EnamelMolar HypomineralizationOral HealthQuality of LifeTooth, DeciduousChild, PreschoolCross-Sectional StudiesFemaleHumansKuwaitMaleMolarPrevalenceDevelopmental enamel defectsEarly childhood cariesEnamel hypoplasiaHypomineralized second primary molarsOral health–related quality of life

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.