Evidence map›Paper›PMID 42633512›Full record

ReviewActas espanolas de psiquiatria2026

Recent Advances in the Brain-Gut Axis in the Development and Progression of Depression.

Meinan Chen, Yanlai Xu

Abstract readReview
In one paragraph

Review in Actas espanolas de psiquiatria, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Meinan ChenDepartment of Traditional Chinese Medicine, Qingdao Special Service Sanatorium of PLA Navy, 266071 Qingdao, Shandong, China.
Yanlai XuDepartment of Traditional Chinese Medicine, Qingdao Special Service Sanatorium of PLA Navy, 266071 Qingdao, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of depression is increasing year by year. Accumulating evidence has shown that the brain-gut axis (BGA) may contribute largely to the development and progression of depression. Gut microbial community composition and metabolites may contribute to the pathophysiological mechanisms of depression by influencing bidirectional communication with the BGA. Gut microbiota dysbiosis has been implicated in the pathogenesis of depression and may provide new potential targets for therapeutic interventions. This article reviews current academic investigations into the association between BGA and depression and discusses how to improve depressive symptoms through the BGA, seeking to offer insights for future research and clinical treatment strategies for depression.

Indexed as

BrainBrain-Gut AxisDepressionDisease ProgressionHumans

Identifiers

PMID42633512
PMCPMC13571194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.