ArticleADMET & DMPK2026
Synthesis of NiO nanostructures as electrode materials for the voltammetric determination of epinephrine in the presence of acetaminophen.
Article in ADMET & DMPK, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Background and purpose: Epinephrine, also called noradrenaline, is an important chemical mediator in the central nervous system of mammals. Experimental approach: The hydrothermally synthesized NiO nanostructures were used for the modification of a screen-printed electrode, and they were characterized and used in this work for the voltammetric determination of epinephrine in the presence of acetaminophen. Several electrochemical techniques were employed to investigate the electrochemical properties of NiO-modified screen-printed carbon electrode, including cyclic voltammetry, differential pulse voltammetry and chronoamperometry. Key results: The differential pulse voltammetry peak current of epinephrine was linear with concentration in the range from 0.01 to 400.0 μmol L Conclusion: Furthermore, the NiO modified screen-printed carbon electrode was successfully applied to quantify epinephrine and acetaminophen in both urine samples and pharmaceutical formulations. The results indicated satisfactory recovery rates for the target analytes. Consequently, this electrode is suitable for the analysis of both compounds in pharmaceutical and clinical laboratory settings.
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