ReviewRegenerative therapy2026
Research advances in microneedle-exosome delivery systems for the treatment of multisystem diseases.
Review in Regenerative therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The combined application of microneedles (MNs) and exosomes represents a significant research direction in the fields of targeted drug delivery and regenerative medicine. Their synergistic and complementary effects not only address key technical challenges associated with exosome delivery-such as low delivery efficiency and limited tissue penetration-but also endow MNs with capabilities for targeted therapy and precise diagnostics, thereby demonstrating substantial advantages in the diagnosis and treatment of multisystem diseases. This review summarizes recent advances in MN-exosome delivery systems across dermatological, cardiovascular and cerebrovascular, and musculoskeletal diseases, as well as tumor diagnosis and therapy, ocular surface disorders, and oral diseases. It focuses on the fabrication strategies, mechanisms of action, and therapeutic efficacy of various MN-based exosome delivery systems. Furthermore, it proposes research perspectives and potential solutions for diseases that respond poorly to conventional diagnostic and therapeutic approaches, providing a reference for the future development and clinical translation of MN-exosome systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.