ArticleCritical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine2026
Association between prior ICU admission for drug overdose and ICU readmission: A retrospective registry-based study.
Article in Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: We aimed to investigate patients discharged alive from hospital following an ICU admission for drug overdose and whether exposure of prior overdose-related ICU admission was associated with a future ICU readmission. Design setting participants: This multicentre registry-based study included data from 167 ICUs across Australia that reported to the Australia New Zealand Intensive Care Society Adult Patient Database. We included all adult patients (≥16 years) discharged alive from the hospital after an ICU admission for an overdose between 1st July 2018 and 31st December 2023. The exposure of interest was an overdose-related ICU admission in the six months prior to the index ICU admission. Main outcome measures: The primary outcome was all-cause ICU readmission within the following six months. The secondary outcome was ICU readmission due to an overdose within six months. We used mixed-effects multivariable logistic regression to adjust for confounders and identify risk factors for ICU readmission. Results: Of 30,125 index episodes of ICU overdose admissions (25,604 individuals), 2555 (8.5%) had an overdose-related ICU admission in the prior six months. They had higher rates of all-cause ICU readmission compared to those without a prior overdose-related ICU admission (40.9% vs. 8.9%; p < 0.001). After accounting for other factors including younger age, female sex, Indigenous status, higher SOFA scores, chronic respiratory disease, cirrhosis, dialysis dependence and frailty, an overdose in the six months prior to the index ICU admission was associated with ICU readmission in the following six months (OR = 1.93; 95%CI: 1.59-2.34; p < 0.001). Conclusions: This large Australian registry-based study found that in patients discharged alive from hospital following an ICU admission for overdose, patients with a history of prior ICU admission for overdose had almost double the risk for ICU readmission. These findings have implications for risk stratification, clinical decision-making and resource planning.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.