Evidence map›Paper›PMID 42633229›Full record

ArticleCurrent developments in nutrition2026

Warning Labels for Nonnutritive Sweeteners: A Randomized Controlled Trial with Chilean Parents.

Aline D'Angelo Campos, Lindsey Smith Taillie, Allison C Sylvetsky, Natalia Rebolledo

Registry-linked trialAbstract read
In one paragraph

Article in Current developments in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06842693 (Evaluating Chile's Proposed Non-nutritive Sweeteners Warning Label Regulation), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06842693 nacompletednot on this map

Evaluating Chile's Proposed Non-nutritive Sweeteners Warning Label Regulation

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2025 to 2025Enrolled3,916ConditionsDiet, HealthyArmsControl, Chilean non-nutritive sweetener label, Colombian non-nutritive sweetener label
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aline D'Angelo CamposCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Lindsey Smith TaillieCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Allison C SylvetskyDepartment of Nutrition, University of Rhode Island, South Kingstown, RI, United States.
Natalia RebolledoCenter for Research in Food Environments and Prevention of Nutrition-Related Chronic Diseases (CIAPEC), Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In Chile, added sugar warning labels prompted product reformulation with nonnutritive sweeteners (NNS). Some countries have since adopted NNS labels to discourage this industry response, but evidence of their effects on consumer behavior is limited. Objectives: This study aimed to examine the impact of 2 types of NNS labels on Chilean parents' NNS-containing product identification, product choices for their children, and product perceptions. Methods: In 2025, 3523 Chilean parents (children age 2-14 y) were randomly assigned to either no NNS label (control), a child-focused NNS warning ("CONTAINS NON-NUTRITIVE SWEETENERS, AVOID CONSUMPTION AMONG CHILDREN"), or an NNS disclosure ("CONTAINS NON-NUTRITIVE SWEETENERS"). Participants viewed sets of 4 products (one without added sweeteners and others with sugar, NNS, or both) and identified NNS-containing products, selected one product for their child, and, afterward, recalled labels seen. Next, participants viewed NNS-containing products and rated labels' perceived message effectiveness (PME), products' perceived healthfulness, and intentions to limit children's NNS intake. Average differential effects (ADEs) are reported in percentage points (pp) or 1 to 5 scales. Results: Both the child-focused NNS warning and NNS disclosure led to higher correct identification of NNS-containing products (ADE = 67 pp; ADE = 69 pp, both Conclusions: Both NNS labels improved parents' NNS-containing product identification and encouraged choice of products without added sugar or NNS for their children.This trial was registered at the clinicaltrials.gov as NCT06842693. https://clinicaltrials.gov/study/NCT06842693.

Indexed as

food labelingfront-of-package labelingfront-of-pack labelingnonnutritive sweetenersnonsugar sweetenerswarning labels

Identifiers

PMID42633229
PMCPMC13499217

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.