ReviewJournal of pharmaceutical analysis2026
Multifunctional MOF composites for advanced drug identification and screening: Innovations, applications and challenges.
Review in Journal of pharmaceutical analysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Metal organic semiconducting structures for electronic band engineering and optoelectronic uses.iScience · 2026Review
- Metal-Organic Frameworks in Food Biotechnology: Opportunities, Challenges, and Future Perspectives for Probiotic Delivery, Precision Fermentation, and Circular Food Systems.Nanomaterials (Basel, Switzerland) · 2026Review
- Cu-based metal-organic frameworks: synthesis, biomedical applications, and beyond.Discover nano · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drug identification and screening are crucial in precision medicine and pharmaceutical research, yet they face challenges such as interference from complex biological matrices, insufficient sensitivity for trace detection, and poor specificity. Multifunctional metal-organic framework (MOF) composites, leveraging their tunable pore structures, high specific surface area, and modular functional integration capabilities, have emerged as promising solutions to address these issues. Despite rapid progress, a systematic review comprehensively consolidating these advances remains absent. This review systematically summarizes the design strategies and performance advantages of four representative types of MOF composites (carbon dots (CDs)-MOFs, magnetic nanoparticles (MNPs)-MOFs, biomacromolecules-MOFs, covalent organic frameworks (COFs)-MOFs), along with their applications in multimodal sensing (fluorescence, electrochemical, colorimetric, and surface-enhanced Raman scattering (SERS)) and high-efficiency screening platforms (offline ligand fishing (LF) and immobilized enzyme microreactors (IMERs)). Collective findings demonstrate that rationally engineered multifunctional MOF composites can significantly meet the stringent requirements of drug analysis regarding sensitivity, selectivity, and stability. This review also provides an in-depth discussion of current challenges and future directions in the field, including stability, structure-activity relationships, biocompatibility, and scalable fabrication, aiming to offer design insights for the development of drug identification and screening technologies and to fill the gap in systematic reviews in this area.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.