Evidence map›Paper›PMID 42633114›Full record

ArticleFood chemistry: X2026

A multi-dimensional engineering strategy integrating computational design, self-cyclization and whole cell biocatalysis for efficient epilactose production.

Shengjie Sun, Jiaming Liu, Xiaolong Gao, Dong Jing, Wenxiao Wang, Qin Yan, Shenyong Shi, Peng Xiong, Xiutao Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shengjie SunSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.
Jiaming LiuSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.
Xiaolong GaoSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.
Dong JingInternational Joint Laboratory on Extremophilic Bacteria and Biological Synthesis, Shandong University of Technology, Zibo 255000, China.
Wenxiao WangSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.
Qin YanSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.
Shenyong ShiInternational Joint Laboratory on Extremophilic Bacteria and Biological Synthesis, Shandong University of Technology, Zibo 255000, China.
Peng XiongSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.
Xiutao LiuSchool of Life Sciences and Medicine, Shandong University of Technology, Zibo 255000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilactose is a promising functional disaccharide, but its biomanufacturing is limited by insufficient enzyme activity, poor thermostability, and costly catalyst preparation. We first used the REME platform to computationally evaluate candidate enzymes. Among them, cellobiose 2-epimerase from

Indexed as

Cellobiose-2-epimeraseEpilactoseProtein cyclizationProtein engineeringWhole-cell biocatalysis

Identifiers

PMID42633114
PMCPMC13499061

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.