ArticleAlzheimer's & dementia (New York, N. Y.)
Sex- and
Francesca Vitali, Adam C Raikes, Simona Merlini, Yuan Shang, Georgina Torrandell-Haro, Gerson D Hernandez, Fei Yin
Abstract read
In one paragraphArticle in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Adam C RaikesCenter for Innovation in Brain Science University of Arizona Tucson Arizona USA.
Simona MerliniCenter for Innovation in Brain Science University of Arizona Tucson Arizona USA.
Yuan ShangCenter for Innovation in Brain Science University of Arizona Tucson Arizona USA.
Georgina Torrandell-HaroCenter for Innovation in Brain Science University of Arizona Tucson Arizona USA.
Gerson D HernandezCenter for Innovation in Brain Science University of Arizona Tucson Arizona USA.
Fei YinCenter for Innovation in Brain Science University of Arizona Tucson Arizona USA.
Funding
Timing of Menopausal Hormone Therapy across Perimenopause to Menopause Transition: Neuroimmune System in BrainP01AG026572 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fei Yin · 2006 to 2026
$53.7MSUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1991 to 2020
$49.1MAllopregnanolone as Regenerative Therapeutic for Alzheimer's: Phase 2 Clinical TrialR01AG063826 · NIA · UNIVERSITY OF ARIZONA · PI BRINTON, ROBERTA EILEEN, RODGERS, KATHLEEN E. · 2019 to 2025
$37.2MResearch Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI REIMAN, ERIC MICHAEL · 2001 to 2020
$32.5MResearch Education ComponentP30AG072980 · NIA · BANNER HEALTH · PI ALIREZA ATRI · 2021 to 2026
$24.9MMulti-omic network-directed proteoform discovery, dissection and functional validation to prioritize novel AD therapeutic targetsU01AG061356 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BENNETT, DAVID ALAN, DE JAGER, PHILIP L · 2018 to 2022
$13.7MPhytoSERM Efficacy to Prevent Menopause Associated Decline in Brain Metabolism and Cognition: A Double-Blind, Randomized, Placebo-Controlled Phase 2 Clinical TrialR01AG075122 · NIA · UNIVERSITY OF ARIZONA · PI ROBERTA EILEEN BRINTON, Gerson David Hernandez · 2022 to 2026
$7.6MSex Differences in the Molecular Determinants of Alzheimer's Disease Risk: Prodromal EndophenotypeR01AG057931 · NIA · UNIVERSITY OF ARIZONA · PI BRINTON, ROBERTA EILEEN, CHANG, RUI · 2018 to 2022
$6.0MDisrupted Lipid Metabolism in Alzheimer's DiseaseRF1AG079157 · NIA · UNIVERSITY OF ARIZONA · PI YIN, FEI · 2024 to 2024
$1.6MAPOE Regulation of Neuron-Astrocyte Metabolic Coupling in Alzheimer's DiseaseRF1AG068175 · NIA · UNIVERSITY OF ARIZONA · PI YIN, FEI · 2021 to 2021
$1.1MNIA NIH HHS P01 AG026572NIA NIH HHS P30 AG010161NIA NIH HHS P30 AG019610NIA NIH HHS P30 AG072980NIA NIH HHS R01 AG057931NIA NIH HHS R01 AG063826NIA NIH HHS R01 AG075122NIA NIH HHS RF1 AG068175NIA NIH HHS RF1 AG079157NIA NIH HHS U01 AG061356
6 · The paper itselfAbstract
Introduction: Alzheimer's disease (AD) risk is strongly modified by biological sex and apolipoprotein E ( Methods: We analyzed frontal cortex RNA sequencing data from 369 individuals in the Religious Orders Study Rush Memory and Aging Project cohort ( Results: Transcriptomic dysregulation varied markedly across groups. Female Discussion: Sex and
Indexed as
Alzheimer's diseaseapolipoprotein E genotypedrug repurposingmedical informaticssex differencestranscriptomics
Identifiers
PMID42633094
PMCPMC13499011
What OpenQuestion holds
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LicenceCC BY-NC-ND
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