Evidence map›Paper›PMID 42633073›Full record

ArticleInternational journal of cardiology. Heart & vasculature2026

Influence of age, frailty and non-cardiac comorbidities on survival in patients undergoing mitral valve edge-to-edge repair - a perspective from the German health care system.

Kerstin Piayda, Nabor Keweloh, Bernhard Unsöld, Samuel Sossalla, Amin Polzin, Fabian Voss, Jafer Haschemi, Marcel Giemsa, Ursula Marschall, Beata Hennig and 3 more

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In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kerstin PiaydaDepartment of Cardiology and Vascular Medicine, University Hospital Giessen and Marburg and Medical Faculty Justus-Liebig-University, Giessen, Germany.
Nabor KewelohDepartment of Cardiology and Vascular Medicine, University Hospital Giessen and Marburg and Medical Faculty Justus-Liebig-University, Giessen, Germany.
Bernhard UnsöldDepartment of Cardiology and Vascular Medicine, University Hospital Giessen and Marburg and Medical Faculty Justus-Liebig-University, Giessen, Germany.
Samuel SossallaDepartment of Cardiology and Vascular Medicine, University Hospital Giessen and Marburg and Medical Faculty Justus-Liebig-University, Giessen, Germany.
Amin PolzinDepartment of Cardiology, Pulmonology and Vascular Medicine, University Hospital and Medical Faculty, Heinrich-Heine University, Duesseldorf, Germany.
Fabian VossDepartment of Cardiology, Pulmonology and Vascular Medicine, University Hospital and Medical Faculty, Heinrich-Heine University, Duesseldorf, Germany.
Jafer HaschemiDepartment of Cardiology, Pulmonology and Vascular Medicine, University Hospital and Medical Faculty, Heinrich-Heine University, Duesseldorf, Germany.
Marcel GiemsaDepartment of Medicine and Health Services Research BARMER Statutory Health Insurance Fund Wuppertal, Germany.
Ursula MarschallDepartment of Medicine and Health Services Research BARMER Statutory Health Insurance Fund Wuppertal, Germany.
Beata HennigDepartment of Medicine and Health Services Research BARMER Statutory Health Insurance Fund Wuppertal, Germany.
Michael BeilDepartment of Medical Intensive Care, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Malte KelmDepartment of Cardiology, Pulmonology and Vascular Medicine, University Hospital and Medical Faculty, Heinrich-Heine University, Duesseldorf, Germany.
Christian JungDepartment of Cardiology, Pulmonology and Vascular Medicine, University Hospital and Medical Faculty, Heinrich-Heine University, Duesseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: The influence of age, frailty, and non-cardiac comorbidities on long-term survival in a large, real-world cohort of patients undergoing mitral valve edge-to-edge-repair (M-TEER) was investigated. In addition, associated healthcare resource utilization and expenditure were evaluated. Methods: Demographic data, data on frailty and co-morbidities were drawn from the anonymized database of the second largest sickness fund in Germany and analysed in regards of long-term survival. Results: Relevant data was available in 4896 patients. Very old patients (80-99 years) had an impaired survival as compared to younger ones (OR 1.2, 95% CI [1.07;1.49], Conclusion: Age, frailty and comorbidities play a significant role in survival prediction of patients undergoing M-TEER. Overall medical expanses did not change after M-TEER however heart failure hospitalizations were less frequent.

Indexed as

AgeClinical outcomesComorbiditiesFrailtyLong-term survivalMitral valve edge-to-edge-repairM-TEER

Identifiers

PMID42633073
PMCPMC13498951

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.