ArticleArchives of Razi Institute2025
Expression Analysis of
Article in Archives of Razi Institute, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Colorectal cancer ranks among the most prevalent types of cancer across the globe, particularly in developing countries. Biomarkers like long non-coding RNAs (lncRNAs) have a key impact in early detection and personalized treatment. This study aimed to compare the expression levels of Materials & Methods: Fifty colorectal cancer tissue samples and fifty non-cancerous polyp tissues, confirmed by a gastroenterologist, were analyzed. RNA was extracted, cDNA was synthesized, and expression levels of Results: A total of 50 participants (22 men and 28 women) were enrolled, with a mean age of 62.56±16.41 years, while the control group consisted of 30 males and 20 females (mean age: 58.41±11.13 years). Expression analysis revealed significantly higher levels of both PVT- 1 lncRNA (fold change=X.X, P<0.05) and TGF-β (fold change=X.X, P<0.05) in colorectal cancer tissues compared to controls. These differences persisted despite demographic imbalances between groups. ROC curve analysis demonstrated the diagnostic potential of both biomarkers in distinguishing cancerous from non-cancerous tissues. Conclusion: Our findings suggest that
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