Evidence map›Paper›PMID 42632919›Full record

ArticleAge and ageing2026

Intrinsic capacity trajectories and health outcomes in home care settings: a Canadian population-based cohort study.

Bonaventure Amandi Egbujie, Hein van Hout, George Heckman, Leon Geffen, John N Morris, John P Hirdes

Abstract read
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Article in Age and ageing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Bonaventure Amandi EgbujieUniversity of Waterloo Faculty Health - School of Public Health Sciences, 200 University Av West, Waterloo, Ontario N2L 3G1, Canada.ORCID 0000-0003-0748-1882
Hein van HoutAmsterdam Public Health Research Institute - Aging and Later Life, Amsterdam, Netherlands.
George HeckmanLawson Health Research Institute, London, Ontario, Canada.
Leon GeffenUniversity of Cape Town - The Albertina and Walter Sisulu Institute of Ageing in Africa, Rondebosch, WC, South Africa.ORCID 0000-0002-9546-5323
John N MorrisHebrew Senior Life - Institute for Aging Research, Boston, MA, USA.
John P HirdesUniversity of Waterloo Faculty Health - School of Public Health Sciences, 200 University Av West, Waterloo, Ontario N2L 3G1, Canada.ORCID 0000-0001-9619-6543

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntrinsic capacity (IC), defined as the composite of physical and mental capacities, is a dynamic indicator of healthy ageing. Understanding its longitudinal patterns may improve risk stratification and inform care planning among home care recipients.

methodsThis population-based retrospective cohort study used routinely collected interRAI Home Care data in Canada. IC was derived across five domains and modelled using group-based trajectory modelling to identify distinct patterns over time. Associations between trajectory membership and key outcomes, including mortality and long-term care (LTC) admission, were examined.

resultsThe study included 302 467 home care recipients; 62.2% were female, with a median age of 81 years (IQR 14). Five distinct IC trajectories were identified, demonstrating substantial heterogeneity in functional ageing. Most individuals followed declining trajectories, while smaller groups remained stable or showed improvement. Cognitive impairment was strongly associated with adverse trajectories, whereas gains were most evident in locomotion and psychological domains. Importantly, baseline IC level alone did not fully capture subsequent outcome heterogeneity. For example, individuals with moderate baseline IC had higher LTC admission than those with low IC who improved (48.4% vs 38.1%), underscoring the importance of longitudinal assessment.

conclusionIC trajectories capture clinically meaningful differences in ageing pathways that are not apparent from single assessments. These findings support the use of routinely collected interRAI data to enable scalable, trajectory-informed care, with implications for earlier intervention, targeted service allocation and improved planning across the continuum of care. Further work is required to translate these findings into practical clinical tools to support early risk stratification at admission and guide future care planning.

Indexed as

AgingHealthy AgingHome Care ServicesAgedAged, 80 and overAge FactorsCanadaCognitionFemaleFunctional StatusGeriatric AssessmentHumansLong-Term CareMaleRetrospective StudiesRisk Factorsageing trajectoryhome careICOPEinterRAIintrinsic capacityolder people

Identifiers

PMID42632919
PMCPMC13499700

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.