Evidence map›Paper›PMID 42632889›Full record

ArticleBMC primary care2026

Assessing the reliability and validity for metabolic syndrome diagnosis using point-of-care analyzers in a mobile setup - a pilot study.

Sanne Houtenbos, Anne Schraplau, Pia-Maria Wippert, Michael Rapp, Heinz Völler, Klaus Bonaventura, Frank Mayer

Abstract readValidation Study
In one paragraph

Article in BMC primary care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sanne HoutenbosMedical Sociology and Psychobiology, Faculty of Human Sciences, University of Potsdam, Am Neuen Palais 10, Potsdam, 14469 , Germany. sanne.houtenbos@uni-potsdam.de.
Anne SchraplauSports Medicine and Sports Orthopedics, University Outpatient Clinic, University of Potsdam, Potsdam, Germany.
Pia-Maria WippertMedical Sociology and Psychobiology, Faculty of Human Sciences, University of Potsdam, Am Neuen Palais 10, Potsdam, 14469 , Germany.
Michael RappSocial and Preventive Medicine, Faculty of Human Sciences, University of Potsdam, Potsdam, Germany.
Heinz VöllerRehabilitation Medicine, University of Potsdam, Potsdam, Germany.
Klaus BonaventuraDepartment of Cardiology, Ernst von Bergmann Hospital, Potsdam, Germany.
Frank MayerSports Medicine and Sports Orthopedics, University Outpatient Clinic, University of Potsdam, Potsdam, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe metabolic syndrome (MetS) is characterized by having three or more of these risk factors: increased blood glucose (Glc), serum triglycerides (TG), blood pressure (BP), waist circumference (WC), and reduced high-density lipoprotein (HDL). Mobile diagnostics using point-of-care (POC) blood analyzers could help identify individuals at risk. This pilot study assessed reliability and validity of MetS risk factor analysis using POC analyzers in a mobile examination unit.

methodsFifty participants (52 ± 7y; 170 ± 10 cm; 80 ± 19 kg, m/f: 21/29) were included for analysis. The mobile examination unit was equipped with different POC analyzers (Alere, LABGEO, CardioChek for Glc, HDL, TG; Quo-Test-A1C Testkit for HbA1c'). Agreement compared to a reference laboratory (RefLab) was analyzed by Bland-Altman (bias, Limits of Agreement (LoA)), ICC, SEM and McNemar's test. Test-retest analysis was assessed on two different days (max. two weeks apart) using Spearman's rho, ICC, test-retest variability (TRV%) and McNemar's test.

resultsBased on the smallest bias and low number of missing values (Glc: -5 [LoA - 25 to 6] mg/dl; TG: 8 [LoA - 58 to 30] mg/dl; HDL: -2 [LoA - 14 to 9] mg/dl), and the highest agreement in MetS diagnosis compared to the results of RefLab, the Alere POC device was chosen. Test-retest reliability (n = 16) for MetS risk factors and HbA1c measured in the mobile setup ranged from poor to excellent with low TRV (0.9-5.8%). Risk factor classification and MetS diagnosis did not differ between measurement days.

conclusionsA mobile setup using the Alere POC analyzer could be used as a valid mobile screening method for MetS to ensure early detection of risk factors.

Indexed as

Metabolic SyndromeMobile Health UnitsPoint-of-Care SystemsAdultBlood GlucoseBlood PressureFemaleGlycated HemoglobinHumansMaleMiddle AgedPilot ProjectsPoint-of-Care TestingRapid Diagnostic TestsReproducibility of ResultsRisk FactorsBlood GlucoseGlycated HemoglobinTriglyceridesHbA1cMetabolic risk factorsMobile examination

Identifiers

PMID42632889
PMCPMC13499312

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.