Observational studyIndian journal of pediatrics2026
Clinical Predictors of High-Flow Nasal Cannula Failure in Children with Acute Respiratory Illness: A Single-Center Experience.
Observational study in Indian journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
High-flow nasal cannula (HFNC) therapy is increasingly used for managing pediatric respiratory distress; however, early identification of children at risk of treatment failure remains challenging. This retrospective observational study evaluated clinical predictors of HFNC failure among children aged 1 mo to 12 y admitted with moderate-to-severe respiratory illness at a tertiary care center between April and June 2025. Fifty children received HFNC therapy, of whom 44 (88%) had successful outcomes, while six (12%) required invasive mechanical ventilation, among these two died. HFNC failure was significantly associated with a Respiratory Severity Score (RSS) ≥10, admission oxygen saturation (SpO
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