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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2026

Predictors of quality of life after cardiac procedures: a mixed-methods study.

Niki Medendorp, Hilda Rijnhart-de Jong, Ilse Verstraaten, Tom Oirbans, Edgar Daeter, Henrico Wesselink, Roel Snijder, Daniela Schulz, Pepijn van der Voort, Christiaan Boerma and 5 more

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Niki Medendorp *Netherlands Heart Registration, Utrecht, The Netherlands. medendorp.nm@gmail.com.
Hilda Rijnhart-de Jong *Hart- en Vaatcentrum, Frisius Medical Center Leeuwarden, Leeuwarden, The Netherlands. hilda.rijnhart@frisiusmc.nl.
Ilse VerstraatenStichting Harteraad, Den Haag, The Netherlands.
Tom OirbansDepartment of Cardiology and Cardiothoracic Surgery, St. Antonius Hospital, Nieuwegein, The Netherlands.
Edgar DaeterDepartment of Cardiology and Cardiothoracic Surgery, St. Antonius Hospital, Nieuwegein, The Netherlands.
Henrico WesselinkDepartment of Cardiology and Cardiothoracic Surgery, Isala Hospital, Zwolle, The Netherlands.
Roel SnijderDepartment of Cardiology and Cardiothoracic Surgery, Isala Hospital, Zwolle, The Netherlands.
Daniela SchulzCatharina Heart Centre, Catharina Hospital, Eindhoven, The Netherlands.
Pepijn van der VoortCatharina Heart Centre, Catharina Hospital, Eindhoven, The Netherlands.
Christiaan BoermaDepartment of Intensive Care, Frisius Medical Center Leeuwarden, Leeuwarden, The Netherlands.
Dennis DuikerMOmenz Foundation for Well-Being and Health, Maarssen, The Netherlands.
Anja MachielseDepartment Humanism and Social Resilience, University of Humanistic Studies, Utrecht, Netherlands.
Machteld HuberInstitute for Positive Health, Utrecht, The Netherlands.
Johanna TakkenbergDepartment of Cardio-Thoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.
Dennis van VeghelNetherlands Heart Registration, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCardiovascular disease has a major impact on patients' lives. Cardiac procedures aim to improve patient health-related quality of life (HRQoL); however, some patients show little to no improvement afterwards. Changes in HRQoL are used to evaluate quality of care, and to enhance shared decision-making. We aimed to explore determinants predictive of HRQoL changes in patients undergoing a cardiac procedure.

methodsA stepwise, mixed-methods study was conducted. First, relevant determinants were identified and selected by performing a literature search and Delphi study. Next, a cross-sectional survey study was conducted among patients who underwent a cardiac procedure. The impact of determinants on changes in HRQoL (measured with the SF36-2/SF12-2, or Effect On Quality-Of-Life Questionnaire (AFEQT)) was examined.

resultsBased on the literature search and Delphi study, 19 determinants were selected and subsequently observed among patients. In total, 1016 patients participated; 731 undergoing a CABG, PCI or SAVR (CPS-group), and 285 undergoing a PVI (PVI-group). In the CPS-group, 9 determinants were associated with significant changes in physical HRQoL and 9 determinants for mental HRQoL were found. In the PVI-group, significant determinants in the four AFEQT domains were found.

conclusionThis study shows that several psychological and social factors are significant predictors for patients' HRQoL after cardiac procedures. Addressing these factors in consultations is considered important when deciding about cardiac procedures. This may allow shared decision making, enhance patient expectations and be beneficial for choosing the most optimal treatment choice for the individual patient.

Indexed as

Cardiac Surgical ProceduresCardiovascular DiseasesQuality of LifeAgedCross-Sectional StudiesDelphi TechniqueFemaleHumansMaleMiddle AgedSurveys and QuestionnairesCardiac procedureDeterminantsHealth-related quality of lifeMixed-methods study

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.