Evidence map›Paper›PMID 42631665›Full record

ArticleMacromolecular bioscience2026

Poly(Amino Acid) Coordination Nanosonosensitizer as a ROS Amplifier for Enhanced Sonodynamic-Chemodynamic Therapy.

Zhe Wang, Jing Tan, Yi Jin, Wenxin Li, Yian Liu, Jiarui Zhang, Xinru Yuan, Heyun Shen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Macromolecular bioscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhe Wang *Beijing Key Laboratory of Green Chemicals Biomanufacturing, College of Life Science and Technology, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, China.
Jing Tan *Beijing Key Laboratory of Green Chemicals Biomanufacturing, College of Life Science and Technology, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, China.
Yi JinBeijing Key Laboratory of Green Chemicals Biomanufacturing, College of Life Science and Technology, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, China.
Wenxin LiBeijing Key Laboratory of Green Chemicals Biomanufacturing, College of Life Science and Technology, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, China.
Yian LiuBeijing Key Laboratory of Green Chemicals Biomanufacturing, College of Life Science and Technology, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, China.
Jiarui ZhangBeijing Key Laboratory of Green Chemicals Biomanufacturing, College of Life Science and Technology, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, China.
Xinru YuanBeijing Key Laboratory of Green Chemicals Biomanufacturing, College of Life Science and Technology, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, China.
Heyun ShenBeijing Key Laboratory of Green Chemicals Biomanufacturing, College of Life Science and Technology, State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, China.ORCID https://orcid.org/0000-0001-7960-3864

Funding

Beijing Natural Science Foundation L212001National Natural Science Foundation of China 51972343National Natural Science Foundation of China 92359202
6 · The paper itself

Abstract

Sonodynamic therapy (SDT) has gained widespread attention owing to its low invasiveness and target specificity. However, developing high biocompatibility sonosensitizers with high sonosensitization efficacy in a tumor hypoxic and reductive microenvironment is still a significant challenge. Herein, we fabricated a poly(amino acid) coordination nanoparticle (PFHCu) as a potent sonosensitizer and dual nanoenzyme with great biocompatibility and high reactive oxygen species (ROS) generation capacity for efficient SDT and chemodynamic therapy (CDT). PFHCu owns dual nanoenzyme properties of CAT and POD-like activities, catalyzing H

Indexed as

Amino AcidsNanoparticlesReactive Oxygen SpeciesUltrasonic TherapyAnimalsDoxorubicinGlutathioneHumansHydrogen PeroxideAmino AcidsDoxorubicinGlutathioneHydrogen PeroxideReactive Oxygen Speciescoordination nanoparticlenanoenzymepoly(amino acid)sonodynamic therapysonosensitizer

Identifiers

PMID42631665
PMCPMC13499536

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.