ArticleJournal of applied physiology (Bethesda, Md. : 1985)2026
Cardiometabolic benefits and risks for transgender youth with the initiation of gender-affirming hormone therapy: a case series.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Interventions for transgender (TG) youth include puberty suppression and gender-affirming hormone therapy (GAHT). Studies have begun to show changes in cardiometabolic outcomes in adolescent transgender males (TGM) and females (TGF). We hypothesized that in TGM and TGF youth, GAHT would increase total cholesterol, low-density lipoprotein cholesterol, insulin resistance (IR), and adiposity while decreasing high-density lipoprotein cholesterol (HDL-C) and endothelium-dependent vasodilation. We measured IR (oral glucose tolerance test), lipid profile, and endothelial function (flow-mediated vasodilation) before and following 6 mo of GAHT in TGM (
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