Evidence map›Paper›PMID 42631280›Full record

ArticleJournal of community hospital internal medicine perspectives2026

Don't Mistake it for RA: A Case of Antithyroid Arthritis Syndrome After Methimazole Initiation.

Michael K Viggiano, Auda Baker, Diana Palanker, Ayrton Bangolo, Anna Belyayeva, Iyad Baker

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of community hospital internal medicine perspectives, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael K ViggianoHackensack Meridian Health Palisades Medical Center Internal Medicine Department, 7600 River Rd, North Bergen, NJ 07047, USA.
Auda BakerHackensack Meridian Health Palisades Medical Center Internal Medicine Department, 7600 River Rd, North Bergen, NJ 07047, USA.
Diana PalankerHackensack Meridian Health Palisades Medical Center Internal Medicine Department, 7600 River Rd, North Bergen, NJ 07047, USA.
Ayrton BangoloHackensack Meridian Health Palisades Medical Center Internal Medicine Department, 7600 River Rd, North Bergen, NJ 07047, USA.
Anna BelyayevaHackensack Meridian Health Palisades Medical Center Internal Medicine Department, 7600 River Rd, North Bergen, NJ 07047, USA.
Iyad BakerHackensack Meridian Health Palisades Medical Center Internal Medicine Department, 7600 River Rd, North Bergen, NJ 07047, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antithyroid arthritis syndrome (AAS) is a rare reaction to thionamides (e.g., methimazole) that can cause sudden, severe joint pain. It often gets mistaken for rheumatoid arthritis or lupus but typically improves within four weeks when the medication is stopped. A 51-year-old man with Graves' disease developed a rash and disabling joint pain in multiple areas within weeks of starting methimazole. Labs showed elevated liver enzymes and CRP, but no autoimmune markers. Symptoms improved quickly after a short steroid taper and stopping the drug. This case shows how AAS can mimic autoimmune disease and why it is important to recognize early to avoid unnecessary treatment.

Indexed as

Antithyroid arthritis syndromeDrug-induced polyarthritisGraves’ diseaseMethimazoleRheumatologic mimicThionamide reaction

Identifiers

PMID42631280
PMCPMC13496498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.