ReviewFrontiers in neurology2026
Shared neuropathological features of mild traumatic brain injury and anesthesia.
Review in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mild traumatic brain injuries are highly prevalent and can produce persistent sequelae, creating substantial personal and societal burdens. Recent evidence suggests that anesthesia administration for extracranial surgeries is both common and potentially problematic following concussive injuries. Despite this concern, few studies have assessed outcomes among concussion patients undergoing surgery, and clinical guidance for this population remains limited. This review examines shared neuropathological features between mild traumatic brain injury and anesthesia to identify potential mechanisms that could underlie poor outcomes following surgery in the setting of concussion. Both mild traumatic brain injury and anesthesia contribute to neuroinflammation and impaired blood-brain barrier function, resulting in neuronal and glial injury. When superimposed on the mechanical injury caused by concussion, these overlapping processes may contribute to secondary injury, delayed recovery, and worse long-term outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.