ArticleAmerican journal of translational research2026
Safety and short-term oncological outcomes of multimodal modified overlap esophagojejunostomy in total laparoscopic total gastrectomy for elderly patients.
Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo compare the safety and short-term oncological outcomes of a multimodal modified Overlap esophagojejunostomy versus the conventional Overlap technique in elderly patients undergoing total laparoscopic total gastrectomy (TLTG).
methodsThis retrospective cohort study enrolled elderly gastric cancer (GC) patients who underwent TLTG combined with D2 lymphadenectomy. Patients were divided into two groups based on the digestive tract reconstruction method adopted: the conventional group (n = 154) receiving traditional Overlap esophagojejunostomy and the modified group (n = 103) receiving multimodal modified Overlap esophagojejunostomy. Perioperative and postoperative indicators were compared between the two groups, including total operative time, esophagojejunostomy time, intraoperative blood loss, postoperative complications, postoperative recovery parameters (time to ambulation, first flatus, and liquid diet initiation), length of hospital stay, two-year recurrence rate, as well as postoperative nutritional markers (albumin [ALB], hemoglobin [Hb]) and inflammatory markers (C-reactive protein [CRP], interleukin-6 [IL-6]).
resultsThe modified group demonstrated significantly shorter total operative time (
conclusionsThe multimodal modified Overlap esophagojejunostomy is a safe and efficient surgical technique for elderly patients undergoing TLTG. It can accelerate postoperative recovery, improve early postoperative nutritional status, and alleviate systemic inflammatory responses, without compromising short-term oncological outcomes.
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