Evidence map›Paper›PMID 42630986›Full record

ArticleACS bio & med chem Au2026

Dimethylindanoylindole Isomers Revealed Different Pharmacological Profiles at CB1 and CB2 Cannabinoid Receptors.

Soo Jung Oh, Ruiru Guo, Christopher Lucaj, Neshira Gutierrez, Kh Tanvir Ahmed, Alexander H Williams, Chang-Guo Zhan, Gregory B Dudley, Hideaki Yano

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS bio & med chem Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Soo Jung OhCenter for Drug Discovery, Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts 02115, United States.
Ruiru GuoCenter for Drug Discovery, Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts 02115, United States.
Christopher LucajCenter for Drug Discovery, Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts 02115, United States.
Neshira GutierrezCenter for Drug Discovery, Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts 02115, United States.
Kh Tanvir AhmedDepartment of Chemistry, West Virginia University, Morgantown, West Virginia 26506, United States.
Alexander H WilliamsDepartment of Pharmaceutical Sciences, University of Kentucky, Lexington, Kentucky 40536, United States.
Chang-Guo ZhanDepartment of Pharmaceutical Sciences, University of Kentucky, Lexington, Kentucky 40536, United States.
Gregory B DudleyDepartment of Chemistry, West Virginia University, Morgantown, West Virginia 26506, United States.
Hideaki YanoCenter for Drug Discovery, Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, Massachusetts 02115, United States.ORCID https://orcid.org/0000-0001-9242-3884

Funding

Training Program on Development of Medications for Substance Use DisorderT32DA055553 · NIDA · NORTHEASTERN UNIVERSITY · PI Raymond G. Booth, Alexandros Makriyannis · 2022 to 2026
$1.3M
NIDA NIH HHS T32 DA055553
6 · The paper itself

Abstract

Synthetic cannabinoid receptor agonists (SCRAs) exhibit higher efficacy and potency at CB1 and CB2 cannabinoid receptors compared to Δ

Indexed as

2,2-DimethylindaneBiased agonismCannabinoid type 1 receptorCannabinoid type 2 receptorSynthetic cannabinoid receptor agonists

Identifiers

PMID42630986
PMCPMC13495017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.