Evidence map›Paper›PMID 42630984›Full record

ArticleACS bio & med chem Au2026

Characterization of a Heme-Binding Radical SAM Enzyme HemW from

Caitlin M Padgett, Melissa M Bollmeyer, Kaleb Boswinkle, Anthony T Iavarone, Valérie de Crécy-Lagard, R David Britt, Wen Zhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS bio & med chem Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Update of
    2026
5 · Who and what money

Authors and funding

7 authors.

Caitlin M PadgettDepartment of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida 32306, United States.ORCID https://orcid.org/0009-0000-8141-7673
Melissa M BollmeyerDepartment of Chemistry, University of California, Davis, California 95616, United States.
Kaleb BoswinkleDepartment of Microbiology & Cell Science, University of Florida, Gainesville, Florida 32603, United States.
Anthony T IavaroneCalifornia Institute for Quantitative Biosciences, University of California, Berkeley, California 94720, United States.
Valérie de Crécy-LagardDepartment of Microbiology & Cell Science, University of Florida, Gainesville, Florida 32603, United States.ORCID https://orcid.org/0000-0002-9955-3785
R David BrittDepartment of Chemistry, University of California, Davis, California 95616, United States.ORCID https://orcid.org/0000-0003-0889-8436
Wen ZhuDepartment of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida 32306, United States.ORCID https://orcid.org/0000-0003-3190-0071

Funding

Supplement:Spectroscopy Investigations of Metalloenzyme MechanismsR35GM126961 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI R. David Britt · 2018 to 2026
$3.7M
Linking gene and function through comparative genomic and experimental approachesR35GM156215 · NIGMS · UNIVERSITY OF FLORIDA · PI Valerie A de Crecy-Lagard · 2025 to 2026
$1.3M
Linking Conformational Dynamics to Activity Impairment of Disease-associated Human EnzymesR35GM160337 · NIGMS · FLORIDA STATE UNIVERSITY · PI Wen Zhu · 2025 to 2026
$835k
High Definition Ion Mobility SpectrometerS10OD020062 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI WILLIAMS, EVAN R · 2015 to 2015
$590k
NIGMS NIH HHS R35 GM126961NIGMS NIH HHS R35 GM156215NIGMS NIH HHS R35 GM160337NIH HHS S10 OD020062
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EPRHDX-MSHemeHemWiron−sulfur clusterradical SAM enzyme

Identifiers

PMID42630984
PMCPMC13495026

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.