Evidence map›Paper›PMID 42630974›Full record

ArticleJBMR plus2026

The distinct roles of PTHrP and PTH1R in long bone growth and digit formation.

Takeshi Shimoide, Loan Nguyen-Yamamoto, Lucie Canaff, Naoyuki Kawao, Yuto Takada, Hiroshi Kaji, Akifumi Enomoto, David Goltzman

Abstract read
In one paragraph

Article in JBMR plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Takeshi ShimoideDepartment of Oral and Maxillofacial Surgery, Kindai University Faculty of Medicine, Osaka 590-0197, Japan.ORCID https://orcid.org/0000-0001-6250-0412
Loan Nguyen-YamamotoResearch Institute of the McGill University Health Centre and Department of Medicine, McGill University, Montreal, Quebec H4A 3J1, Canada.ORCID https://orcid.org/0009-0002-7505-2481
Lucie CanaffResearch Institute of the McGill University Health Centre and Department of Medicine, McGill University, Montreal, Quebec H4A 3J1, Canada.ORCID https://orcid.org/0000-0002-3311-6144
Naoyuki KawaoDepartment of Physiology and Regenerative Medicine, Kindai University Faculty of Medicine, Osaka 590-0197, Japan.ORCID https://orcid.org/0000-0002-4148-5476
Yuto TakadaDepartment of Oral and Maxillofacial Surgery, Kindai University Faculty of Medicine, Osaka 590-0197, Japan.ORCID https://orcid.org/0009-0009-2293-350X
Hiroshi KajiDepartment of Physiology and Regenerative Medicine, Kindai University Faculty of Medicine, Osaka 590-0197, Japan.ORCID https://orcid.org/0000-0001-7433-5135
Akifumi EnomotoDepartment of Oral and Maxillofacial Surgery, Kindai University Faculty of Medicine, Osaka 590-0197, Japan.ORCID https://orcid.org/0000-0001-5804-8283
David GoltzmanResearch Institute of the McGill University Health Centre and Department of Medicine, McGill University, Montreal, Quebec H4A 3J1, Canada.ORCID https://orcid.org/0000-0003-3421-7147

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PTH-related peptide (PTHrP) and its receptor, the PTH/PTHrP receptor type 1 (PTH1R), are essential for chondrocyte differentiation and epiphyseal cartilage homeostasis. To evaluate the functional differences between PTHrP and PTH1R derived from mesenchymal progenitor cells (MPCs) in skeletal development, we generated MPC-specific

Indexed as

digit patterningmesenchymal progenitor cellsmorphogenesisparathyroid hormoneparathyroid hormone-related proteinreceptorskeletal developmenttype 1

Identifiers

PMID42630974
PMCPMC13496395

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.