ArticleInternational journal of nanomedicine2026
Iodine-125-Labeled Graphdiyne Enables Photothermal-Enhanced Radiosensitization for Synergistic Therapy of Esophageal Cancer.
Jiahao Huang, Shufeng Liang, Min Zhang, Yue Zheng, Chunyan Wang, Xin Tian, Bin Yang
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In one paragraphArticle in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Jiahao Huang *Department of Thoracic Surgery, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, People's Republic of China.
Shufeng Liang *Department of Molecular Biology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, People's Republic of China.
Min ZhangDepartment of Molecular Biology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, People's Republic of China.
Yue ZhengDepartment of Molecular Biology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, People's Republic of China.
Chunyan WangDepartment of Molecular Biology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, People's Republic of China.
Xin TianState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Jiangsu Key Laboratory of Radiation Injury Prevention and Hazardous Substance Control, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, People's Republic of China.ORCID 0000-0002-5631-8160 Bin YangDepartment of Thoracic Surgery, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, People's Republic of China.
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No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Purpose: Iodine-125 ( Methods: A polymeric peptide-functionalized graphdiyne (GDY) nanoplatform (GDY-PEG-PTyr) was constructed by conjugating an amphiphilic PEG-PTyr copolymer (prepared by ring-opening polymerization of tyrosine N-carboxyanhydride) onto GDY nanosheets, followed by Results: GDY-PEG-PTyr exhibited a two-dimensional sheet-like morphology, a high radiolabeling yield (~95%), and radiochemical stability above 80% over 72 h, and it reached mild hyperthermia (42-45 °C) with reproducible photothermal output over repeated heating-cooling cycles. In vitro, the combined GDY-PEG-PTyr- Conclusion: The GDY-PEG-PTyr-
Indexed as
Esophageal NeoplasmsGraphiteIodine RadioisotopesPhotothermal TherapyRadiation-Sensitizing AgentsAnimalsBrachytherapyCell Line, TumorCell SurvivalFemaleHumansMiceMice, Inbred BALB CMice, NudeReactive Oxygen SpeciesGraphiteIodine-125Iodine RadioisotopesRadiation-Sensitizing AgentsReactive Oxygen Speciesbrachytherapyesophageal cancergraphdiyneiodine-125photothermal therapyradiosensitization
Identifiers
PMID42630968
PMCPMC13496252
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