Evidence map›Paper›PMID 42630878›Full record

ArticleACS measurement science au2026

A Single-Enzyme Electrochemical Biosensor for Lactose Detection in Human Breastmilk and Dairy Products.

Raquel Sánchez-Salcedo, Donna T Geddes, Nicolas H Voelcker

Abstract read
In one paragraph

Article in ACS measurement science au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raquel Sánchez-SalcedoDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.ORCID https://orcid.org/0000-0002-5335-1088
Donna T GeddesAustralian Research Council Training Centre for Next-Gen Biomedical Analysis, Perth, Western Australia 6009, Australia.
Nicolas H VoelckerDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.ORCID https://orcid.org/0000-0002-1536-7804

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactose, a disaccharide found predominantly in human breast milk and dairy products, plays a vital role in human health and nutrition. While lactose is an essential energy source particularly for infant growth, it is also a biomarker of low milk production in breastfeeding women. Furthermore, lactose intolerance affects a substantial portion of the global population, impacting the quality of life. Therefore, the ability to detect and quantify lactose is important as a biomarker for both milk production and nutritional content. Here, we report on the development of a single-enzyme electrochemical biosensor for lactose employing lactose oxidase (LOx), which converts lactose to lactobionic acid and hydrogen peroxide. The sensor showed high specificity, achieving a limit of detection of 1.4 μM. The analytical performance of the sensor was verified in human breast milk as well as bovine milk. This approach allows for a rapid, reliable, and potentially portable platform for lactose detection, making it ideal for both clinical applications and routine controls in the food industry.

Indexed as

dairy productselectrochemical sensorhuman breast milklactose detectionpoint-of-care diagnosticssingle-enzyme sensing platform

Identifiers

PMID42630878
PMCPMC13495733

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.