ReviewFrontiers in nutrition2026
Dietary total antioxidant capacity and risk of breast cancer: a systematic review and dose-response meta-analysis of observational studies.
Review in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Background: Numerous epidemiological studies have suggested a potential association between the antioxidant capacity of the diet and the risk of breast cancer. Yet, these studies have yielded inconclusive results. We therefore conducted a systematic review and dose-response meta-analysis of observational studies to ascertain the association between dietary total antioxidant capacity (TAC) and breast cancer risk. Methods: We systematically searched PubMed, Embase, Scopus, ISI Web of Science and China National Knowledge Infrastructure (CNKI) from database inception to May 2026, using predefined keywords to identify the relevant articles. Random-effects or fixed-effects models were used to pool relative risks (RRs) with corresponding 95% confidence intervals (CIs), as appropriate. Heterogeneity across studies was estimated using Cochran's Q test and the I Results: Nine observational studies (seven case-control and two cohort studies), encompassing 33,981 participants, were included in the meta-analysis. Higher dietary TAC intake was significantly associated with a lower risk of breast cancer (RR = 0.86; 95%CI: 0.76-0.98; Conclusions: This study indicates that higher dietary TAC intake is associated with a reduced risk of breast cancer. Further well-designed longitudinal studies are warranted to confirm these findings.
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