Evidence map›Paper›PMID 42630667›Full record

ArticleOncology letters2026

Probable cavernous sinus-adjacent meningeal metastasis from esophageal squamous cell carcinoma: A case report.

Heng Di Zhang, Bin He, Jing Jing Peng, Ting Yu, Fang Yuan Kong, Ling Zhang

Abstract readCase Reports
In one paragraph

Article in Oncology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Heng Di ZhangDepartment of Ophthalmology, The General Hospital of Western Theater Command of the Chinese People's Liberation Army, Chengdu, Sichuan 610083, P.R. China.
Bin HeDepartment of Oncology, The General Hospital of Western Theater Command of The Chinese People's Liberation Army, Chengdu, Sichuan 610083, P.R. China.
Jing Jing PengDepartment of Oncology, The General Hospital of Western Theater Command of The Chinese People's Liberation Army, Chengdu, Sichuan 610083, P.R. China.
Ting YuDepartment of Pathology, The General Hospital of Western Theater Command of the Chinese People's Liberation Army, Chengdu, Sichuan 610083, P.R. China.
Fang Yuan KongDepartment of Oncology, The General Hospital of Western Theater Command of The Chinese People's Liberation Army, Chengdu, Sichuan 610083, P.R. China.
Ling ZhangDepartment of Oncology, The General Hospital of Western Theater Command of The Chinese People's Liberation Army, Chengdu, Sichuan 610083, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meningeal dissemination from esophageal squamous cell carcinoma (ESCC) is exceptionally rare, and cavernous sinus-adjacent involvement has been only sparsely described. The present study reports the case of a 59-year-old man with controlled extracranial ESCC who presented with acute oculomotor and trochlear nerve palsies shortly after severe acute respiratory syndrome coronavirus 2 infection. Although the symptoms were initially attributed to post-viral neuropathy, contrast-enhanced magnetic resonance imaging demonstrated multifocal nodular meningeal enhancement and irregular dural thickening adjacent to the cavernous sinus, findings highly suggestive of meningeal metastasis. Cerebrospinal fluid examination and biopsy of the meningeal lesion were not performed; therefore, the diagnosis remained as radiologically supported probable meningeal metastasis from ESCC, and the exact pachymeningeal or leptomeningeal compartment could not be confirsmed. The progression occurred 2 months after resection of a solitary brain metastasis despite sustained extracranial control. This case illustrates sequential parenchymal and probable meningeal central nervous system progression and highlights the risk of anchoring bias when a concurrent viral infection provides an apparently plausible alternative explanation. New focal cranial neuropathies in patients with cancer warrant urgent contrast-enhanced neuroimaging.

Indexed as

brain metastasiscavernous sinuscranial nerve palsyesophageal squamous cell carcinomameningeal metastasis

Identifiers

PMID42630667
PMCPMC13495053

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.