Evidence map›Paper›PMID 42630536›Full record

ArticleDigital health

Health halo effect in supplement marketing: A content analysis of unregulated medical claims in community pharmacies.

Marwan Alrasheed, Saad Alobid, Mohammed Almasoud, Basmah Alfageh, Rawan Almadfaa, Reema Almoqran, Abdulaziz Alkhonizan, Aliyah Almobarak, Faisal Nasser, Musab Gari and 1 more

Abstract read
In one paragraph

Article in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marwan AlrasheedDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0001-8504-3779
Saad AlobidDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Mohammed AlmasoudRegulatory & Government Affairs, Pharma Pharmaceutical Industries & Biological Products.
Basmah AlfagehDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0003-3051-9017
Rawan AlmadfaaDepartment of Pharmacy Practice, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0002-8751-7648
Reema AlmoqranDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Abdulaziz AlkhonizanDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Aliyah AlmobarakDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Faisal NasserDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Musab GariJames L. Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH, United States.
Abdulrahman AlsuhibaniDepartment of Pharmacy Practice, College of Pharmacy, Qassim University, Qassim, Saudi Arabia.ORCID https://orcid.org/0000-0003-4852-1166

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dietary supplements are widely promoted online, often using persuasive health claims that may contribute to the "health halo effect," where consumers may infer unproven therapeutic benefits. In Saudi Arabia, the rise of online listings by nutraceutical and dietary supplement companies has amplified the visibility of such claims, raising questions about their regulatory compliance. Objective: To examine the nature and regulatory risk of health-related claims in dietary supplements marketed by nutraceutical and dietary supplement companies through Saudi pharmacy websites and assess their alignment with SFDA guidelines. Methods: A cross-sectional content analysis was conducted on 209 supplement products which yielded 251 distinct health-related claims extracted from leading Saudi pharmacy websites. Claims were thematically categorized and assessed using a rule-based natural language processing (NLP) classifier aligned with Saudi Food and Drug Authority (SFDA) regulatory tiers. Each claim was assigned a risk level of low, medium, or high, based on language and references to medical conditions. A verb frequency analysis was conducted to explore linguistic patterns. Chi-square testing was used to examine the association between claim categories and regulatory risk. Results: Of the 251 claims analyzed, 173 (68.9%) were classified as low risk, 7 (2.8%) as medium risk, and 71 (28.3%) as high risk. The most common claim categories were bone/joint health (14%), immune support (10%), general wellness/wellbeing (10%), hair/skin/nails (7%), energy/fatigue (7%), antioxidant/detox (6%), and cardiovascular health (6%). High-risk claims were most concentrated in categories related to bone/joint health, general wellness, and cardiovascular support. The most frequent action verbs were "support," "improve," and "treat." A significant association was observed between claim category and regulatory risk level (p < 0.001). Conclusion: A substantial proportion of supplement claims implies therapeutic benefit. Strengthening regulatory oversight and consumer education is essential to mitigate the health halo effect and ensure safe supplement use.

Indexed as

attitude to healthherbalpatient attitudepublic healthsupplements

Identifiers

PMID42630536
PMCPMC13494279

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.