ArticleF&S reports2026
Delayed diagnosis and treatment of Sheehan syndrome: a case report.
Article in F&S reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To report a case of Sheehan syndrome diagnosed and treated nearly 2 decades after a postpartum hemorrhage. Design: Case report. Subjects: A 45-year-old woman presenting with nonspecific symptoms found to have severe hyponatremia and panhypopituitarism 1 month after immigrating from China and 17 years after a postpartum hemorrhage. Exposure: Hormone replacement with hydrocortisone, levothyroxine, and combined oral contraceptive pills. Main Outcome Measures: Clinical and laboratory assessment of central adrenal insufficiency, hypothyroidism, and hypogonadotropic hypogonadism after initiation of treatment. Results: After initiation of hydrocortisone and levothyroxine, the hyponatremia and nonspecific symptoms, including fatigue, dyspnea, nausea, vomiting, myalgias, and brain fog, improved rapidly. Pituitary magnetic resonance imaging demonstrated markedly reduced pituitary volume. Dual-energy x-ray absorptiometry scanning revealed osteopenia. The patient has had 9 months of treatment with cyclic combined oral contraceptive pills without hormonal withdrawal bleeding. Overall, she reports significant improvement in quality of life. Conclusion: Postpartum hypopituitarism is widely underdiagnosed with nonspecific presentations and limited access to care contributing to diagnostic delay. Clinicians must maintain a high index of suspicion to diagnose hypopituitarism after a postpartum hemorrhage, even years after delivery. Early initiation of hormone replacement therapy is essential in patients with postpartum hypopituitarism for protection of cardiovascular and bone health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.