ArticleAmerican journal of translational research2026
Combined prognostic value of the neutrophil-to-lymphocyte ratio and serum lactate for 28-day mortality in patients with sepsis-induced pulmonary dysfunction.
Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo investigate the predictive value of the neutrophil-to-lymphocyte ratio (NLR) combined with serum lactate (Lac) in patients with sepsis-induced pulmonary dysfunction (SIPD) for early evaluation and personalized treatment.
methodsA total of 230 SIPD patients were retrospectively screened from January 2018 to December 2023. After exclusions, 226 patients were classified into the survivor group (154 cases) and the non-survivor group (72 cases) based on their 28-day survival status. Receiver operating characteristic (ROC) curves assessed NLR-Lac combined prognostic value for 28-day mortality in SIPD, with logistic regression screening risk factors.
resultsIn the non-survivor group, levels of NLR, serum Lac, sequential organ failure assessment (SOFA) score, acute physiology and chronic health evaluation II (APACHE II) score, C-reactive protein (CRP), procalcitonin (PCT), white blood cells (WBC), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and creatinine (Cr) were higher (all
conclusionCombined NLR and Lac detection may improve prognostic accuracy in SIPD patients.
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