SynthesisFrontiers in neuroscience2026
Transcranial ultrasound stimulation for post-stroke dysfunction: a meta-analysis of randomized controlled trials.
Synthesis in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To systematically evaluate the efficacy of transcranial ultrasound stimulation (TUS) in improving neurological deficits, motor, cognitive, swallowing function, and activities of daily living (ADL) in stroke patients. Methods: PubMed, Embase, Web of Science, Cochrane Library, CNKI, and Wanfang Database were searched for randomized controlled trials (RCTs) on TUS for stroke patients from inception to December 1, 2025. Two reviewers independently conducted literature screening, data extraction, risk of bias assessment using the Cochrane tool, and methodological quality evaluation using the PEDro scale. Meta-analysis was performed with RevMan 5.3, and publication bias was assessed using Egger's test in Stata 18.0. Results: Twenty-one RCTs involving 1,748 patients were included. TUS combined with conventional rehabilitation significantly improved neurological deficits (NIHSS: MD = -1.98, 95% CI: -3.61 to -0.34, Conclusion: Current evidence supports that TUS combined with rehabilitation effectively promotes recovery of neurological, motor, cognitive, swallowing, and daily living functions in stroke patients, with particular value for those with moderate-to-severe dysfunction. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD420261296388.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.