Evidence map›Paper›PMID 42630318›Full record

ArticleFrontiers in plant science2026

Multi-omics analysis reveals the phenylalanine pathway associated with stem development under organic and compound fertilizers in

Jiujun Du, Yongxia Bai, Zhuohan Gao, Yu Zhao, Jihan Cui, Min Zhang, Fengyan Cao, Meihong Huang, Shunguo Li, Xueyan Xia

Abstract read
In one paragraph

Article in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiujun Du *Institute of Millet Crops, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory of Genetic Improvement and Utilization for Featured Coarse Cereals (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs/The Key Research Laboratory of Minor Cereal Crops of Hebei Province, Shijiazhuang, China.
Yongxia Bai *State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of National Forestry and Grassland Administration, Research Institute of Forestry, Chinese Academy of Forestry, Beijing, China.
Zhuohan GaoInstitute of Millet Crops, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory of Genetic Improvement and Utilization for Featured Coarse Cereals (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs/The Key Research Laboratory of Minor Cereal Crops of Hebei Province, Shijiazhuang, China.
Yu ZhaoInstitute of Millet Crops, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory of Genetic Improvement and Utilization for Featured Coarse Cereals (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs/The Key Research Laboratory of Minor Cereal Crops of Hebei Province, Shijiazhuang, China.
Jihan CuiInstitute of Millet Crops, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory of Genetic Improvement and Utilization for Featured Coarse Cereals (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs/The Key Research Laboratory of Minor Cereal Crops of Hebei Province, Shijiazhuang, China.
Min ZhangInstitute of Millet Crops, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory of Genetic Improvement and Utilization for Featured Coarse Cereals (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs/The Key Research Laboratory of Minor Cereal Crops of Hebei Province, Shijiazhuang, China.
Fengyan CaoInstitute of Millet Crops, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory of Genetic Improvement and Utilization for Featured Coarse Cereals (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs/The Key Research Laboratory of Minor Cereal Crops of Hebei Province, Shijiazhuang, China.
Meihong HuangInstitute of Millet Crops, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory of Genetic Improvement and Utilization for Featured Coarse Cereals (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs/The Key Research Laboratory of Minor Cereal Crops of Hebei Province, Shijiazhuang, China.
Shunguo LiInstitute of Millet Crops, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory of Genetic Improvement and Utilization for Featured Coarse Cereals (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs/The Key Research Laboratory of Minor Cereal Crops of Hebei Province, Shijiazhuang, China.
Xueyan XiaInstitute of Millet Crops, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory of Genetic Improvement and Utilization for Featured Coarse Cereals (Co-Construction by Ministry and Province), Ministry of Agriculture and Rural Affairs/The Key Research Laboratory of Minor Cereal Crops of Hebei Province, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: To explore the mechanism underlying the effects of combined application of organic fertilizer and compound fertilizer on stem development of foxtail millet, this study used ' Methods: The effects of different fertilizer treatments were analyzed by integrating phenotypic determination, microscopic observation of stem structure, and multi-omics analyses including transcriptomics, metabolomics, and proteomics. Results: The results showed that compared with the sole application treatments, the combined application treatment significantly promoted phenotypic indicators of foxtail millet such as plant height, stem diameter, and stem fresh weight, and also significantly increased the cross-sectional area of stem vessels, the cell wall thickness of basic tissues, and the stem puncture strength. Multi-omics analyses revealed that differentially expressed genes (DEGs), differentially accumulated metabolites (DAMs), and differentially expressed proteins (DEPs) under the combined application treatment were significantly enriched in pathways related to cell wall development, such as phenylalanine metabolism and phenylpropanoid biosynthesis. Specifically, mapped to the phenylalanine pathway, the expression levels of key genes, metabolites, and proteins including Discussion: This study suggests that the combined application of organic fertilizer and compound fertilizer is associated with enhanced stem structural properties (including increased vascular area, cell wall thickness, and stem puncture strength) potentially linked to improved lodging resistance, with the phenylalanine pathway emerging as a candidate pathway, providing a theoretical basis and technical support for optimizing fertilization strategies and improving yield stability in the high-yield cultivation of foxtail millet.

Indexed as

cell wallcow dungfoxtail milletmulti-omicsphenylalanine

Identifiers

PMID42630318
PMCPMC13493561

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.