Trial reportFrontiers in psychiatry2026
Peripheral magnetic stimulation effects on brain activity in older adults with schizophrenia - a randomized controlled pilot study.
Trial report in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07194460 (Effects of Combined Exercise and Peripheral Magnetic Stimulation on Biopsychosocial Functional Impairments in Older Adults With Schizophrenia), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Combined Exercise and Peripheral Magnetic Stimulation on Biopsychosocial Functional Impairments in Older Adults With Schizophrenia
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To conduct an exploratory neurophysiological pilot analysis of transient resting-state EEG alterations induced by a single peripheral magnetic stimulation (PMS) session in older adults with schizophrenia. Methods: In a randomized sham-controlled study, 40 older inpatients received either active PMS (30 minutes on the quadriceps) or a sham intervention. Eyes-closed resting-state EEG (59 channels) was recorded pre- and post-intervention. Spectral power (δ, θ, α, β, γ), scalp topographies, and weighted phase lag index (dwPLI) functional connectivity were analyzed. Results: Active PMS induced significant, frequency-specific changes: decreased δ/θ power and increased α/β/γ power. Topographically, low-frequency reductions were prominent in the midline-right hemisphere, while high-frequency enhancements occurred in frontoparietal regions. Connectivity analyses revealed a dual pattern: potentially strengthened long-range δ-θ coupling (frontal/midline to right posterior) and enhanced short-range high-frequency synchrony in frontal and lateral parietal areas. These dwPLI connectivity findings derive from exploratory analyses and were not prespecified formal study outcomes. The sham group showed no comparable changes. Conclusions: This exploratory pilot study identified transient band-specific resting-state EEG shifts following one PMS session, including reduced low-frequency oscillations and elevated high-frequency power and connectivity in older adults with schizophrenia. These preliminary neurophysiological patterns require replication in larger controlled trials; no definitive clinical therapeutic inferences can be drawn from this small exploratory dataset. Significance: This exploratory pilot analysis offers preliminary novel electrophysiological observations of PMS-related brain rhythm modulation in older adults with schizophrenia. These exploratory findings lay a foundation for future larger, confirmatory neurophysiological trials peripheral magnetic stimulation; schizophrenia; resting-state EEG; older adults. Clinical trial registration: ClinicalTrials.gov, identifier NCT07194460.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.