Evidence map›Paper›PMID 42630245›Full record

ReviewFrontiers in medicine2026

Signaling pathway networks in frozen shoulder fibrosis: from inflammatory initiation to fibrotic progression.

Tianyu Guo, Yuhui Hua, Xin Liu, Bo Hu, Chenwen Wang, Jinbing He, Wei Zhou

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tianyu Guo *Department of Orthopedics, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yuhui Hua *Department of Orthopedics, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xin LiuDepartment of Orthopedics, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Bo HuDepartment of Orthopedics, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chenwen WangDepartment of Orthopedics, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jinbing HeDepartment of Orthopedics, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wei ZhouDepartment of Orthopedics, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frozen shoulder, also known as adhesive capsulitis, is characterized by fibrosis, thickening, and contracture of the shoulder joint capsule. Through a systematic review of existing research, we have analyzed the complex molecular network of shoulder fibrosis. Previous studies have found that the disease begins with inflammation of the nuclear factor kappa B (NF-κB) and leptin/Janus kinase/signal transducer and activator of transcription (JAK-STAT) pathways, and the transforming growth factor-beta (TGF-

Indexed as

fibrosisfrozen shouldermolecular mechanismsNF-κBsignalingTGF-β

Identifiers

PMID42630245
PMCPMC13493305

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.