Evidence map›Paper›PMID 42630162›Full record

ArticleFrontiers in immunology2026

Structured peptides as vaccine antigens against infections.

Claudia Trappetti, Hugo van Ingen, Mattia Falconi, Alice Romeo, Giada Sancamillo, Marco Caprini, Marco Rinaldo Oggioni, Marco Sette

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Claudia TrappettiDepartment of Pharmacy and Biotechnology FABIT, University of Bologna, Bologna, Italy.
Hugo van IngenNMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands.
Mattia FalconiDepartment of Biology, University of Rome "Tor Vergata", Rome, Italy.
Alice RomeoDepartment of Biology, University of Rome "Tor Vergata", Rome, Italy.
Giada SancamilloEuropean School of Molecular Medicine (SEMM), Milan, Italy.
Marco CapriniDepartment of Pharmacy and Biotechnology FABIT, University of Bologna, Bologna, Italy.
Marco Rinaldo OggioniDepartment of Pharmacy and Biotechnology FABIT, University of Bologna, Bologna, Italy.
Marco SetteINFN, University of Rome "Tor Vergata", Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The onset of a new infection by a pathogen requires a rapid and prompt response from the body. Here, we present a simple and effective strategy to stimulate antibody production by grafting immunogenic peptides onto a beta-strand peptide scaffold. Analysis of the method using a known immunogenic region, the disulfide loop of the PilA protein of the

Indexed as

Antigens, BacterialFimbriae ProteinsPeptidesPseudomonas aeruginosaPseudomonas InfectionsPseudomonas VaccinesAnimalsAntibodies, BacterialEpitopesFimbriae, BacterialMiceProtein Subunit VaccinesAntibodies, BacterialAntigens, BacterialEpitopesFimbriae ProteinsPeptidesProtein Subunit VaccinesPseudomonas Vaccinesdisulfide loopepitope graftingepitope mimicryPseudomonas aeruginosatype IV pilivaccine

Identifiers

PMID42630162
PMCPMC13493254

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.