Evidence map›Paper›PMID 42630156›Full record

ArticleFrontiers in cardiovascular medicine2026

Integrated analysis of MYH6, MYH7, and MYH7B expression and their associated microRNAs in human end-stage heart failure.

Zdenko Červenák, Filip Červenák, Simona Valášková, Nikola Chomaničová, Nikoleta Katreničová, Michal Hulman, Andrea Gažová, Jan Kyselovic

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In one paragraph

Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zdenko Červenák5th Department of Internal Medicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Filip ČervenákDepartment of Genetics, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.
Simona ValáškováInstitute of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Nikola Chomaničová5th Department of Internal Medicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Nikoleta KatreničováInstitute of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Michal HulmanDepartment of Cardiac Surgery, Faculty of Medicine, Comenius University and National Institute of Cardiovascular Diseases (NÚSCH), Bratislava, Slovakia.
Andrea GažováInstitute of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Jan KyselovicInstitute of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac contractility is regulated by two myosin heavy chain (MHC) protein isoforms, Aim: This study aimed to comprehensively analyse the expression profiles of Subjects and methods: The relative expression of these transcripts was measured using RT-qPCR in left ventricular samples from 5 non-failing controls and 24 patients with end-stage heart failure, including hypertrophic cardiomyopathy (HCM, Results: Statistical analysis of independent RNA-seq datasets confirmed strong correlations among Conclusion: Our results suggest that

Indexed as

end-stage heart failureMHRTMYH7MYH7bmyomiRmyosin heavy chainSOX6transcript ratio

Identifiers

PMID42630156
PMCPMC13493238

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.