Enhancing the anticancer potential of garlic and lemon essential oils through nanoemulsification: a comparative study.

Eman M Elgendy, Lobna Shelbaya, Eman M Ramadan, Ashraf R El-Zainy

Abstract readComparative Study

In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Eman M ElgendyDepartment of Home Economy, Faculty of Specific Education, Mansoura University, Mansoura, Egypt. emanelgendy@mans.edu.eg.

Lobna ShelbayaDepartment of Home Economy, Faculty of Specific Education, Mansoura University, Mansoura, Egypt.

Eman M RamadanDepartment of Home Economy, Faculty of Specific Education, Mansoura University, Mansoura, Egypt.

Ashraf R El-ZainyDepartment of Home Economy, Faculty of Specific Education, Mansoura University, Mansoura, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Garlic and lemon essential oils are recognized for their health benefits, and this study analyzed their chemical composition using gas chromatography-mass spectrometry. This study emphasized reducing these oils to nanoemulsion forms. Both conventional and nanoemulsified oils were assessed for their effects on breast cancer cells (MCF-7). Results indicated that both normal and nano garlic essential oils exhibited a pronounced anticancer effect, resulting in lower cell viability. In contrast, lemon essential oils showed moderate efficacy with higher cell viability. The DPPH assay demonstrated that nano garlic essential oil had the strongest antioxidant capacity, while also preserving acid and peroxide values better than traditional forms. Lemon essential oil displayed some effectiveness but was less potent overall. The study concludes that reducing garlic and lemon essential oils to the nanoscale enhances their efficacy, particularly highlighting garlic's volatile oils as a potentially valuable remedy for human health compared with lemon's.

Indexed as

Antineoplastic AgentsAntineoplastic Agents, PhytogenicCitrusGarlicOils, VolatilePlant OilsAntioxidantsCell SurvivalEmulsionsGas Chromatography-Mass SpectrometryHumansMCF-7 CellsAntineoplastic AgentsAntineoplastic Agents, PhytogenicAntioxidantsEmulsionslemon oilOils, VolatilePlant OilsAntioxidantEssential oilsGarlicLemonNanoemulsion

Identifiers

PMID42629371

DOI10.1038/s41598-026-65811-y

PMCPMC13498585

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.