Retinal detachment complicating ocular coloboma.

Choroidal, optic disc and crystalline lens colobomas are rare ophthalmological conditions, but they can (either directly or by association) present with retinal detachments that are difficult to manage. Due to their rarity and variability of presentation, evidence of different approaches to treatment strategies is mainly found in case reports or small case series. This article reviews the basic pathogenesis of these conditions and the authors' experience in how various treatment options address the underlying mechanisms. Sub-categories of retinal detachments complicating choroidal coloboma and management strategies are discussed-principally those where retinal detachment is secondary to choroidal coloboma and those where the management of retinal detachment is complicated by the co-existence of choroidal coloboma. The pathogenesis, natural history and management strategies for retinal detachment associated with optic disc pit are reviewed together with the additional challenges posed by lens and zonular coloboma in the management of retinal detachment.