Evidence map›Paper›PMID 42629146›Full record

ArticleJournal of clinical periodontology2026

Can Artificial Intelligence Match Human Expertise in Long-Term Periodontal Prognosis? A Comparative Accuracy Study.

Pablo Antonio López-Galindo, Giuseppe Troiano, Matteo Serroni, Debora R Dias, Pasquale Santamaría, Luigi Nibali, Gustavo Avila-Ortiz, Andrea Ravidà

Abstract readComparative Study
In one paragraph

Article in Journal of clinical periodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pablo Antonio López-GalindoDepartment of Periodontics and Preventive Dentistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0009-0006-5983-6517
Giuseppe TroianoDepartment of Medicine and Surgery, LUM University, Casamassima, Italy.ORCID https://orcid.org/0000-0001-5647-4414
Matteo SerroniDepartment of Periodontics and Preventive Dentistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-2081-6651
Debora R DiasDepartment of Periodontics and Preventive Dentistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-5387-1753
Pasquale SantamaríaPeriodontology Unit, Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, UK.ORCID https://orcid.org/0000-0003-4102-1759
Luigi NibaliPeriodontology Unit, Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, UK.ORCID https://orcid.org/0000-0002-7750-5010
Gustavo Avila-OrtizDepartment of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Harvard University, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5763-0201
Andrea RavidàDepartment of Periodontics and Preventive Dentistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-3029-8130

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare the prognostic performance of an artificial intelligence (AI) model with that of experienced clinicians in predicting tooth loss over a 10-year period. MATERIALS AND

methodsAn AI model trained on structured clinical and radiographic data was compared with 12 periodontists and 11 general dentists (GDs), who independently assigned prognostic scores (0-10 scale) to 300 teeth with known 10-year outcomes. AI and clinician performance were evaluated under a fixed threshold and group-specific optimal thresholds. Accuracy, sensitivity, specificity, predictive values, area under the receiver operating characteristic curve and calibration were used for comparison.

resultsUsing the fixed threshold (score > 5 = survival), clinicians achieved higher overall accuracy than AI (75.6% periodontists, 74.9% GDs, 69.2% AI; p < 0.05), with sensitivity low and comparable across groups (14.7%-22.7%). Using group-specific optimal thresholds, AI achieved the highest accuracy for all-cause tooth loss (67.5%) and performed comparably to GDs for periodontitis-related tooth loss (76.2% vs. 76.3%). Calibration was substantially worse for AI (Brier score 0.247) than for periodontists and GDs (0.171, 0.170). Individually, AI performance overlapped with that of several clinicians.

conclusionClinicians outperformed AI under a fixed threshold, but AI performance was comparable to clinicians using optimal thresholds, situating AI within the range of experienced clinicians despite modest overall predictive ability.

Indexed as

Artificial IntelligenceClinical CompetencePeriodontal DiseasesPeriodonticsTooth LossFemaleHumansPrediction AlgorithmsPredictive Learning ModelsPredictive Value of TestsPrognosisROC CurveSensitivity and Specificityartificial intelligenceclinical decision support systemperiodontitisprognosistooth loss

Identifiers

PMID42629146
PMCPMC13658045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.