In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
22 authors.
Xibo WangSchool of Materials Science and Engineering, Tsinghua University, Beijing 100084, P. R. China.ORCID 0000-0001-8489-7342 Ningxin ZhuNational Engineering Laboratory for Digital and Material Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing 100081, P. R. China.ORCID 0000-0003-0891-3042 Haitao ChenNational Engineering Laboratory for Digital and Material Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing 100081, P. R. China.ORCID 0000-0001-9757-4307 Bingbing YuSchool of Materials Science and Engineering, Tsinghua University, Beijing 100084, P. R. China.ORCID 0009-0002-6130-1328 Xue GaoMegaRobo Technologies Co. Ltd., Beijing 100085, P. R. China.
Helin LiBeijing Engineering Research Center of Mixed Reality and Advanced Display, School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, P. R. China.ORCID 0009-0001-4359-3980 Can YangSchool of Materials Science and Engineering, Tsinghua University, Beijing 100084, P. R. China.ORCID 0009-0002-1226-8461 Man QinNational Engineering Laboratory for Digital and Material Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing 100081, P. R. China.ORCID 0000-0001-5791-3319 Yuanhao ZhangCentral Laboratory, Peking University School and Hospital of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, NHC Key Laboratory of Digital Stomatology, NMPA Key Laboratory for Dental Materials, and Peking University School and Hospital of Stomatology, Beijing 100084, P. R. China.
Hui QiBeijing Research Institute of Traumatology and Orthopaedics, Beijing Jishuitan Hospital, Beijing 100035, P. R. China.
He DingBeijing Engineering Research Center of Mixed Reality and Advanced Display, School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, P. R. China.ORCID 0000-0002-0884-3112 Xiumei WangSchool of Materials Science and Engineering, Tsinghua University, Beijing 100084, P. R. China.
Liliang OuyangDepartment of Mechanical Engineering, Tsinghua University, Beijing 100084, P. R. China.ORCID 0000-0003-4177-8698 Yuguang WangNational Engineering Laboratory for Digital and Material Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing 100081, P. R. China.ORCID 0000-0002-6754-3689 Xianfeng PingCentral Laboratory, Peking University School and Hospital of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, NHC Key Laboratory of Digital Stomatology, NMPA Key Laboratory for Dental Materials, and Peking University School and Hospital of Stomatology, Beijing 100084, P. R. China.ORCID 0009-0009-7406-4481 Huachun WangSchool of Integrated Circuits, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, P. R. China.ORCID 0000-0003-0731-227X Ludan ZhangNational Engineering Laboratory for Digital and Material Technology of Stomatology, Peking University School and Hospital of Stomatology, Beijing 100081, P. R. China.ORCID 0000-0003-3531-6171 Lan YinSchool of Materials Science and Engineering, Tsinghua University, Beijing 100084, P. R. China.ORCID 0000-0001-7306-4628 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Critical-sized bone defects pose substantial clinical challenges, requiring both regenerative and diagnostic strategies for effective treatment. Here, we report a biodegradable, multifunctional cranial device based on three-dimensional printing. The device integrates a self-electrified scaffold based on a transient zinc-molybdenum battery and an impedance sensor for simultaneous electrical stimulation and continuous assessment of bone healing. The beneficial effects of electrical cues are attributed to elevated calcium ion influx, reactive oxygen species signaling, and up-regulated osteogenesis-related genes. In a rodent cranial defect model, the device promotes osteogenesis while enabling dynamic tracking of early tissue regeneration through impedance measurements. The increase in impedance is associated with enhanced collagen deposition and matrix mineralization. By uniting therapeutic stimulation with in situ monitoring, this work offers a platform for intelligent bone repair with broad potential in regenerative medicine.
Indexed as
Absorbable ImplantsBone RegenerationPrinting, Three-DimensionalSkullWound HealingAnimalsBiocompatible MaterialsHumansOsteogenesisRatsTissue EngineeringTissue ScaffoldsBiocompatible Materials
Identifiers
PMID42627921
PMCPMC13496206
What OpenQuestion holds
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LicenceCC BY-NC
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