Evidence map›Paper›PMID 42627916›Full record

ArticleScience advances2026

Multilocus basis of incipient reproductive isolation in hybridizing populations is revealed by pangenomic and epigenetic divergence.

Angelo A Ruggieri, Francesco Cicconardi, Nicolò Bellin, Stephen H Montgomery, James Mallet, Steven M Van Belleghem, Owen W McMillan, Brian A Counterman, Riccardo Papa

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Angelo A RuggieriDepartment of Biology, University of Puerto Rico, Rio Piedras, Puerto Rico.ORCID 0000-0003-1427-2667
Francesco CicconardiSchool of Biological Sciences, Bristol University, Bristol, United Kingdom.
Nicolò BellinDepartment of Biology, University of Puerto Rico, Rio Piedras, Puerto Rico.ORCID 0000-0001-7451-5398
Stephen H MontgomerySchool of Biological Sciences, Bristol University, Bristol, United Kingdom.ORCID 0000-0002-5474-5695
James MalletOrganismal and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0002-3370-0367
Steven M Van BelleghemEcology, Evolution, and Conservation Biology, Biology Department, KU Leuven, Leuven, Belgium.ORCID 0000-0001-9399-1007
Owen W McMillanSmithsonian Tropical Research Institute, Panama, Panama.ORCID 0000-0003-2805-2745
Brian A CountermanDepartment of Biological Sciences, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0003-2724-071X
Riccardo PapaDepartment of Biology, University of Puerto Rico, Rio Piedras, Puerto Rico.ORCID 0000-0002-7986-9993

Funding

SCIENCE AND TECHNOLOGY COMPETENCY & EDUCATION CORE (STCE)P20GM103475 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Jose R. Rodriguez-Medina · 2012 to 2026
$52.9M
Tracking and Evaluation CoreU54GM133807 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI PORTER, JAMES T. · 2020 to 2024
$17.7M
NIGMS NIH HHS P20 GM103475NIGMS NIH HHS U54 GM133807
6 · The paper itself

Abstract

Incipient reproductive isolation in the presence of gene flow has traditionally been attributed to a small number of major-effect loci under strong selection. Here, using the

Indexed as

Epigenesis, GeneticGenomicsHybridization, GeneticReproductive IsolationAnimalsGene FlowGenetics, PopulationGenetic VariationMutationSelection, Genetic

Identifiers

PMID42627916
PMCPMC13496208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.