Evidence map›Paper›PMID 42627914›Full record

ArticleScience advances2026

Impacts of land use and fallowing on coccidioidomycosis incidence in California: A population-based longitudinal study.

Alexandra K Heaney, Isabel J Jones, Simon K Camponuri, Jennifer R Head, Amanda K Weaver, Philip A Collender, Gail Sondermeyer Cooksey, Seema Jain, Duc Vugia, John Balmes and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alexandra K HeaneyHerbert Wertheim School of Public Health and Longevity Science, University of California, San Diego, San Diego, CA 92093, USA.ORCID 0000-0001-5104-5418
Isabel J JonesDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0003-1821-9177
Simon K CamponuriDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0003-3787-170X
Jennifer R HeadDepartment of Epidemiology, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0003-1449-4171
Amanda K WeaverDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA 94720, USA.
Philip A CollenderDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0003-1130-7123
Gail Sondermeyer CookseyInfectious Diseases Branch, California Department of Public Health, Richmond, CA 94804, USA.ORCID 0000-0002-3019-4470
Seema JainInfectious Diseases Branch, California Department of Public Health, Richmond, CA 94804, USA.
Duc VugiaInfectious Diseases Branch, California Department of Public Health, Richmond, CA 94804, USA.
John BalmesDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-2246-7002
Ellen A EisenDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-5114-5264
Adeyemi AdebiyiDepartment of Life and Environmental Sciences, University of California, Merced, Merced, CA 95343, USA.ORCID 0000-0001-7091-6872
John TaylorDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-5794-7700
Abinash BhattachanDepartment of Geosciences, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-7102-8233
Justin V RemaisDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-0223-4615

Funding

Integrating Epidemiologic and Environmental Approaches to Understand and Predict Coccidioides Exposure and Coccidioidomycosis EmergenceR01AI148336 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI REMAIS, JUSTIN V · 2020 to 2024
$4.5M
Using massive, multi-regional EHR data to estimate the impacts of environmental and other risk factors on fungal disease epidemiology in the U.S.R01AI176770 · NIAID · UNIVERSITY OF MISSOURI KANSAS CITY · PI Mark Hoffman, Justin V Remais · 2023 to 2026
$3.2M
NCEZID CDC HHS U01 CK000539NIAID NIH HHS R01 AI148336NIAID NIH HHS R01 AI176770
6 · The paper itself

Abstract

Coccidioidomycosis (Valley fever) is a growing public health concern in the western U.S., with California reporting more than an eightfold rise in cases over the past two decades. As climate change, groundwater regulation, and prolonged drought drive major agricultural land-use shifts in the state, including widespread retirement of cultivated lands (i.e., fallowing), understanding their effects on this soil-borne fungal infection is critical. We linked 65,657 confirmed, geolocated cases (2008-2021) to high-resolution maps distinguishing natural vegetation, crop types, and fallowed fields to quantify how land use and land cover were associated with disease rates. Flexible statistical models showed that natural land covers, shrubland, barren ground, and grassland, were associated with higher incidence. Some agricultural uses (grain/hay, field crops, corn, and cotton) were associated with higher incidence, whereas others (orchards, rice, and truck crops/berries) were associated with lower incidence. Recently fallowed land (1 to 4 years) was linked to higher incidence, but the effect depended on prior cultivation. These findings indicate that land use changes may inadvertently impact coccidioidomycosis risk, underscoring the need for dust control and other measures to protect communities.

Indexed as

AgricultureCoccidioidomycosisCaliforniaCrops, AgriculturalHumansIncidenceLongitudinal Studies

Identifiers

PMID42627914
PMCPMC13496200

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.