In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Ryan D R BrownDepartment of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0000-0003-2880-0301 Cynthia WeigelDepartment of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0000-0003-3132-4203 Yadu VijayanDepartment of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0009-0009-2036-0699 Katarzyna M TycDepartment of Biostatistics, School of Public Health, Virginia Commonwealth University, Richmond, VA 23298, USA.
Christiane CarterBioinformatics Shared Resource, Massey Comprehensive Cancer Center, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0000-0003-4956-7991 Christopher D GreenDepartment of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0000-0002-7983-7449 Sarah SpiegelDepartment of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0000-0003-0751-2634 Funding
Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Renato Martins · 1985 to 2026
$51.0MUM1HG006348: Cas9 Genome Integrity Supplemental ProposalUM1HG006348 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI Jason D. Heaney, Chih-Wei Logan Hsu · 2016 to 2026
$47.5MNoradrenergic mechanisms in breathing and respiratory pathophysiologiesR01HL130249 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI RAY, RUSSELL S · 2016 to 2024
$5.3MMETABOLIC IMPACTS OF TYPE II INTERFERON SIGNALS IN OBESITYR01DK114356 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI HARTIG, SEAN · 2017 to 2025
$4.6MSphingosine kinase 2 in sexual dimorphism of hepatocellular carcinomaR01CA266124 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI GREEN, CHRISTOPHER D, SPIEGEL, SARAH · 2022 to 2025
$1.9MIns and outs of the bioactive sphingolipid metabolite sphingosine-1-phosphateR35GM152058 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI SARAH SPIEGEL · 2024 to 2026
$1.2MNCI NIH HHS P30 CA016059NCI NIH HHS R01 CA266124NHGRI NIH HHS UM1 HG006348NHLBI NIH HHS R01 HL130249NIDDK NIH HHS R01 DK114356NIGMS NIH HHS R35 GM152058
6 · The paper itselfAbstract
Obesity increases circulating levels of the bioactive sphingolipid metabolite sphingosine-1-phosphate (S1P). Here, we identify adipocyte-expressed sphingosine kinase 2 (SPHK2), an enzyme that produces S1P, as a regulator of adipose tissue browning. Mice with adipocyte-specific deletion of
Indexed as
AdipocytesAdipocytes, BrownAdipose Tissue, BrownPhosphotransferases (Alcohol Group Acceptor)AnimalsEnergy MetabolismInsulin ResistanceLysophospholipidsMaleMiceMice, KnockoutObesitySphingosineSphingosine KinaseThermogenesisLysophospholipidsPhosphotransferases (Alcohol Group Acceptor)Sphingosinesphingosine 1-phosphateSphingosine Kinasesphingosine kinase 2, mouse
Identifiers
PMID42627910
PMCPMC13496211
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