Evidence map›Paper›PMID 42627886›Full record

ArticleScience advances2026

End-to-end all-optical in-sensor computing system using photonic integrated circuits.

Zian Xiao, Zhihao Ren, Yangyang Zhuge, Zixuan Zhang, Yan Yang, Bowei Dong, Chengkuo Lee

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zian XiaoDepartment of Electrical & Computer Engineering, National University of Singapore, 4 Engineering Drive 3, Singapore 117576, Singapore.ORCID 0000-0002-1659-5921
Zhihao RenDepartment of Electrical & Computer Engineering, National University of Singapore, 4 Engineering Drive 3, Singapore 117576, Singapore.ORCID 0000-0002-2520-0784
Yangyang ZhugeDepartment of Electrical & Computer Engineering, National University of Singapore, 4 Engineering Drive 3, Singapore 117576, Singapore.ORCID 0009-0003-4000-3986
Zixuan ZhangDepartment of Electrical & Computer Engineering, National University of Singapore, 4 Engineering Drive 3, Singapore 117576, Singapore.ORCID 0000-0001-5020-7606
Yan YangKey Laboratory of Fabrication Technologies for Integrated Circuits, Chinese Academy of Sciences, Beijing 100029, China.ORCID 0000-0002-0940-7013
Bowei DongInstitute of Microelectronics (IME), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-02, Singapore 138634, Singapore.ORCID 0000-0002-4122-0953
Chengkuo LeeDepartment of Electrical & Computer Engineering, National University of Singapore, 4 Engineering Drive 3, Singapore 117576, Singapore.ORCID 0000-0002-8886-3649

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photonic sensors play an increasingly important role in chemical analysis, but conventional systems rely on sequential wavelength scanning and extensive electronic post-processing, leading to large data redundancy, high latency, and excessive energy consumption. Here, we introduce an end-to-end all-optical in-sensor computing system based on photonic integrated circuits that merges sensing and computing in the optical domain. The system integrates a photonic waveguide sensor and a microring weight bank on a single chip for linear processing, while nonlinear activation is implemented using an erbium-doped fiber amplifier. By performing spectral compression, this system enables real-time optical-domain computing with up to 6-bit precision. The system achieves a classification accuracy of 94.2% across 27 liquid-mixture classes and concentration prediction for mixture chemicals. Compared with conventional photonic sensing systems, the proposed architecture reduces inference latency by a factor of 4.48 and energy consumption by a factor of 11.47. These results establish a compact, low-redundancy, and energy-efficient paradigm for intelligent photonic sensing at the edge.

Identifiers

PMID42627886
PMCPMC13496192

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.