Evidence map›Paper›PMID 42627860›Full record

Trial reportJournal of the International Society of Sports Nutrition2026

Effects of folic acid combined with resistance training on body composition and blood biomarkers in adult males.

Chaowei Yang, Mingming Huang, Haiyuan Zhou, Haoyang Sun, Qi Wang, Ruoxin Yin, Jian Wu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chaowei YangSchool of Kinesiology and Health, Capital University of Physical Education and Sports, Beijing, China.ORCID 0009-0005-0011-8716
Mingming HuangSchool of Kinesiology and Health, Capital University of Physical Education and Sports, Beijing, China.
Haiyuan ZhouSchool of Kinesiology and Health, Capital University of Physical Education and Sports, Beijing, China.
Haoyang SunSchool of Kinesiology and Health, Capital University of Physical Education and Sports, Beijing, China.
Qi WangSchool of Kinesiology and Health, Capital University of Physical Education and Sports, Beijing, China.
Ruoxin YinSchool of Kinesiology and Health, Capital University of Physical Education and Sports, Beijing, China.
Jian WuSchool of Kinesiology and Health, Capital University of Physical Education and Sports, Beijing, China.ORCID 0000-0001-6690-4561

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to investigate the effects of folic acid supplementation combined with resistance training on body composition, homocysteine (Hcy), and lipid-related biomarkers in adult males.

methodsForty healthy male college students were recruited and randomly divided into four groups: control, resistance training (RT), folic acid supplementation (FA), and resistance training + folic acid supplementation (RF) condition (

resultsRegarding body composition, the RF produced the greatest increase in skeletal muscle mass (SMM; + 4.79 ± 2.42 kg), which was significantly larger than the increases observed in the control (+0.96 ± 1.50 kg), FA (+1.03 ± 1.68 kg), and RT (+0.91 ± 1.12 kg) (all

conclusionsFolic acid supplementation combined with resistance training was associated with greater gains in skeletal muscle mass, greater reductions in body fat mass, lower Hcy, and higher HDL-C than either intervention alone. These favorable biomarker changes may contribute to a reduced risk of cardiovascular disease; however, these findings should be interpreted as preliminary rather than definitive evidence of cardiometabolic benefit.

Indexed as

Body CompositionDietary SupplementsFolic AcidResistance TrainingAdultBiomarkersHomocysteineHumansLipidsMaleMuscle, SkeletalYoung AdultBiomarkersFolic AcidHomocysteineLipidsblood lipidsbody compositionFolic acidhomocysteinresistance training

Identifiers

PMID42627860
PMCPMC13501745

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.