Evidence map›Paper›PMID 42627713›Full record

ArticleJMIR research protocols2026

The Effects of AI-Guided Exercise and a Smart Ring on Arterial Stiffness: Protocol for a Randomized Controlled Trial.

Heikki Pentikäinen, Sofia Strömmer, Drake Caraker, Julia Kosonen, Aleksi Rantanen, Saila Hiltunen, Pirjo Komulainen, Heidi Similä, Massimiliano de Zambotti, Kai Savonen and 1 more

Abstract readClinical Trial Protocol
In one paragraph

Article in JMIR research protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Heikki PentikäinenKuopio Research Institute of Exercise Medicine, Yliopistonrinne 3, Kuopio, 70210, Finland.ORCID 0000-0002-4585-7329
Sofia StrömmerOura Science, Oura Health Oy, Elektroniikkatie 10, Oulu, 90590, Finland, 358 407193660.ORCID 0000-0001-7344-1630
Drake CarakerOura Science, Ouraring Inc, San Francisco, CA, United States.ORCID 0009-0009-5639-7899
Julia KosonenOura Science, Oura Health Oy, Elektroniikkatie 10, Oulu, 90590, Finland, 358 407193660.ORCID 0009-0001-2953-0596
Aleksi RantanenOura Science, Oura Health Oy, Elektroniikkatie 10, Oulu, 90590, Finland, 358 407193660.ORCID 0009-0004-7736-4600
Saila HiltunenKuopio Research Institute of Exercise Medicine, Yliopistonrinne 3, Kuopio, 70210, Finland.ORCID 0009-0003-8866-7079
Pirjo KomulainenKuopio Research Institute of Exercise Medicine, Yliopistonrinne 3, Kuopio, 70210, Finland.ORCID 0000-0002-7934-3465
Heidi SimiläOura Science, Oura Health Oy, Elektroniikkatie 10, Oulu, 90590, Finland, 358 407193660.ORCID 0000-0003-0241-1957
Massimiliano de ZambottiOura Science, Ouraring Inc, San Francisco, CA, United States.ORCID 0000-0002-0057-5977
Kai SavonenKuopio Research Institute of Exercise Medicine, Yliopistonrinne 3, Kuopio, 70210, Finland.ORCID 0000-0002-6871-8153
Pauli OhukainenOura Science, Oura Health Oy, Elektroniikkatie 10, Oulu, 90590, Finland, 358 407193660.ORCID 0000-0002-0919-7204

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular disease (CVD) prevention is limited by the major challenge of low long-term adherence to effective lifestyle regimens. Arterial stiffness (measured by carotid-femoral pulse wave velocity [cfPWV]) and maximal cardiorespiratory fitness (measured by VO Objective: We will study the comparative effectiveness of a wearable and an interactive app-based AI coaching intervention promoting moderate exercise in improving gold-standard cfPWV and VO Methods: This randomized controlled trial will recruit 165 eligible sedentary participants aged 30 to 65 years. The co-primary outcomes, cfPWV and VO Results: The recruitment for the study began in October 2024 and will end when 165 men and women have been recruited. Data collection for the study is scheduled to conclude in early 2026. Data management is ongoing. Conclusions: This study will evaluate whether a potentially highly scalable, AI-based coaching intervention can achieve comparable gains in cardiovascular structural health (cfPWV) and functional capacity VO

Indexed as

Cardiovascular DiseasesExerciseVascular StiffnessAdultAgedCardiorespiratory FitnessFemaleHigh-Intensity Interval TrainingHumansMiddle AgedPulse Wave AnalysisRandomized Controlled Trials as Topicarterial stiffnesscardiovascular agehigh-intensity interval trainingpulse wave velocityrandomized controlled trialstudy protocol

Identifiers

PMID42627713
PMCPMC13495994

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.